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DLL4

DLL4 詳細

英語名	Delta-like protein 4	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
研究＆開発段階	Phase 3 Clinical

英語名	Delta-like protein 4
ターゲットの別称	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 3 Clinical

DLL4 製品リスト

属性
Protein (10)Cell Grade Beads (4)Kits (2)
製品ライブラリ
オンライン (16)
種
Human (13)- (3)
タグ
Fc Tag (6)His Tag (1)His Tag & Avi Tag (2)- (6)Fc Tag & Avi Tag (1)
マーカー
Unconjugated (7)Biotin-labeled (3)- (6)

製品番号	種	発現システム	製品説明
HOT DL4-H5255	Human	HEK293	Human DLL4 Protein, Fc Tag, premium grade (Flagship)
HOT DL4-H5259	Human	HEK293	Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
HOT DL4-H82E6	Human	HEK293	Biotinylated Human DLL4 Protein, His,Avitag™, premium grade
HOT GMP-DL4H23	Human	HEK293	GMP Biotinylated Human DLL4 Protein, His,Avitag™
HOT GMP-DL4H27	Human	HEK293	GMP Human DLL4 Protein, Fc Tag (Flagship)
HOT GMP-DL4H28	Human	HEK293	GMP Human DLL4 Protein, Fc Tag
HOT MBS-C013	Human	-	ActiveMax® Human DLL4 μBeads, premium grade (for cells)
DL4-H5227	Human	HEK293	Human DLL4 Protein, His Tag, low Endotoxin (MALS verified)
DL4-H5256	Human	HEK293	Human DLL4 Protein, Fc Tag, Research Grade (Flagship)
DL4-H82F7	Human	HEK293	Biotinylated Human DLL4 Protein, Fc,Avitag™, premium grade

総数量16

DLL4バックグランド

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4分子の別称

DLL4,Delta4

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Tovecimig	ES-104; NOV-1501; CTX-009; HD-B001A; HDB001A; TR-009; ABL001; ABL-001	Phase 3 Clinical	Abl Bio Inc	Ampullary Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Gallbladder Neoplasms; Glioblastoma; Rectal Neoplasms; Solid tumours	詳細
Navicixizumab	OMP-305B83	Phase 3 Clinical	Oncomed Pharmaceuticals Inc	Colorectal Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms	詳細
Dilpacimab	ABT-165; DVD-Ig ABT-165	Phase 1 Clinical	Abbvie Inc	Neoplasms; Solid tumours	詳細

レビュー

A***r2025-11-15
0評価
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
I have been using ACRO Biosystems products since 2021, especially DLL4 Fc proteins (DL4-H5259), refer to our published article: https://pubmed.ncbi.nlm.nih.gov/37795096/, where we have used Acro-products and obtained excellent results. I am very satisfied with the consistent quality and reliability of ACRO’s products. Thanks, Ankit Tanwar Staff Scientist AECOM, NY
Z***a2022-07-06
1評価
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!