DNase I(50U/μl)
Cat. No. DNI-B52H3
DNase I 詳細
Molecule Name
Deoxyribonuclease 1
分子の別称
DNase I,Deoxyribonuclease-1,Deoxyribonuclease I
Drug Development Progress
治験薬の数1
市販薬剤の数1
研究＆開発段階Approved
ターゲットの別称
EC:3.1.21.1，Deoxyribonuclease I，Dornase alfa，DNase I， Lysosomal，DNase I，DNL1，DNASE1，Deoxyribonuclease 1，DRNI，Human Urine Deoxyribonuclease I，Deoxyribonuclease-1，EC 3.1.21.1
バックグランド
Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).
DNase I 製品リスト
Species
- Bovine（1）
Tag
- His Tag（1）
Host
- HEK293（1）
Conjugate
- Unconjugated（1）
Grade
- RUO（1）
Low Endotoxin
- No（1）
| Molecule | Cat. No. | Product Name | 種 | Host | Structure | Purity | Activity | Size&Price |
|---|---|---|---|---|---|---|---|---|
| DNase I | DNase I(50U/μl) |  Bovine | HEK293 | $48.00 1000U |
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治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| repurposed deoxyribonuclease I (Human Microbiology Institute) | Clinical | Alzheimer Disease | 詳細 |
市販薬剤に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | オリジナル製品名 | 最初に承認をした国 | 最初の適応症 | 最初に承認を受けた会社 | 承認された日付 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|---|---|---|---|---|
| Chorionic Gonadotropin | LDI-200 | Approved | Angiogene Pharmaceuticals | Prostatic Neoplasms; Leukemia, Myeloid, Acute; Infertility, Female; Hypogonadism; Cryptorchidism | 詳細 |
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