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EMMPRIN

EMMPRIN 詳細

英語名	Basigin	市販薬剤の数	1
治験薬の数	4	ターゲットの別称	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
研究＆開発段階	Approved

英語名	Basigin
ターゲットの別称	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
市販薬剤の数	1
治験薬の数	4
研究＆開発段階	Approved

EMMPRIN 製品リスト

属性
Protein (6)
製品ライブラリ
オンライン (6)
種
Human (4)Mouse (1)Cynomolgus (1)
タグ
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)
マーカー
Unconjugated (3)Biotin-labeled (2)FITC Labeled (1)

製品番号	種	発現システム	製品説明
HOT CD7-H5222	Human	HEK293	Human EMMPRIN / CD147 Protein, His Tag (MALS verified)
HOT CD7-H82E0	Human	HEK293	Biotinylated Human EMMPRIN / CD147 Protein, Avitag™,His Tag (MALS verified)
HOT CD7-M82E8	Mouse	HEK293	Biotinylated Mouse EMMPRIN / CD147 Protein, His,Avitag™ (MALS verified)
CD7-H5259	Human	HEK293	Human EMMPRIN / CD147 Protein, Fc Tag
CD7-HF222	Human	HEK293	FITC-Labeled Human EMMPRIN / CD147 Protein, His Tag
CD7-C52H8	Cynomolgus	HEK293	Cynomolgus EMMPRIN / CD147 Protein, His Tag (MALS verified)

総数量6

EMMPRINバックグランド

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

EMMPRIN分子の別称

Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Mertuzumab		Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19)	詳細
Meplazumab	HI6H8	Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Coronavirus Disease 2019 (COVID-19); Malaria; Malaria, Falciparum; Post-Acute COVID-19 Syndrome	詳細
humanized ADCC cHAb18 antibody (Pacific Meinuoke/Fourth Military Medical University)		Phase 1 Clinical	Air Force Medical University	Carcinoma, Non-Small-Cell Lung	詳細
CD147-CAR T cell therapy (Peking University People's Hospital)		Phase 1 Clinical	Peking University People'S Hospital	Lymphoma, T-Cell	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Iodine[131I] Metuximab		Approved	Chengdu Huasun Biotechnology Co Ltd	Licartin, 利卡汀	Mainland China	Carcinoma, Hepatocellular	Chengdu Huasun Biotechnology Co Ltd	2006-10-12	Carcinoma, Hepatocellular	詳細