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Fc gamma RI / CD64

Fc gamma RI / CD64 Overview

English Name	High affinity immunoglobulin gamma Fc receptor I	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	IgG Fc Receptor I，FcgammaRIa，High Affinity Immunoglobulin Gamma Fc Receptor I，Fc-Gamma Receptor I A1，CD64 Antigen，CD64A，CD64，FCG1，FCGR1，IGFR1，FcRI，Fc-gamma RIA，Fc-gamma RI，Fc Fragment Of IgG Receptor Ia，Fc Fragment Of IgG， High Affinity Ia， Receptor (CD64)，Fc Gamma Receptor Ia，FCGR1A，Fc Fragment Of IgG， High Affinity Ia， Receptor For (CD64)
Highest Development Stage	Preclinical

English Name	High affinity immunoglobulin gamma Fc receptor I
Target Synonym	IgG Fc Receptor I，FcgammaRIa，High Affinity Immunoglobulin Gamma Fc Receptor I，Fc-Gamma Receptor I A1，CD64 Antigen，CD64A，CD64，FCG1，FCGR1，IGFR1，FcRI，Fc-gamma RIA，Fc-gamma RI，Fc Fragment Of IgG Receptor Ia，Fc Fragment Of IgG， High Affinity Ia， Receptor (CD64)，Fc Gamma Receptor Ia，FCGR1A，Fc Fragment Of IgG， High Affinity Ia， Receptor For (CD64)
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

Fc gamma RI / CD64 Product List

Product Category
Protein (8)Cell (4)Kits (1)
Product Status
Launched (13)
Species
Mouse (2)Human (7)Cynomolgus (2)Canine (1)Rat (1)
Tag
His Tag (5)His Tag & Avi Tag (3)- (5)
Conjugate
Unconjugated (5)Biotin-labeled (3)- (5)

Cat. No.	Species	Host	Product Description
HOT FCA-H52H1	Human	HEK293	Human Fc gamma RI / CD64 Protein, His Tag (SPR & MALS verified)
HOT FCA-H82E8	Human	HEK293	Biotinylated Human Fc gamma RI / CD64 Protein, His,Avitag™ (SPR & MALS verified)
HOT SCJUR-STF072	Human	Jurkat	Human CD64 (Luc) Jurkat Reporter Cell
HOT CD4-R52H3	Rat	HEK293	Rat Fc gamma RI / CD64 Protein, His Tag (MALS verified)
HOT FCA-C52H8	Canine	HEK293	Canine Fc gamma RI / CD64 Protein, His Tag (MALS & SPR verified)
FRT-03	Human	-	Human Fc gamma RI / CD64 binding Kit (TR-FRET)
SCCHO-ATP062H	Human	CHO	CHO/Human CD64 Stable Cell Line (High Expression)
SCCHO-ATP062L	Human	CHO	CHO/Human CD64 Stable Cell Line (Low Expression)
SCCHO-ATP062M	Human	CHO	CHO/Human CD64 Stable Cell Line (Medium Expression)
CD4-M5227	Mouse	HEK293	Mouse Fc gamma RI / CD64 Protein, His Tag (MALS verified)

Total: 13

Fc gamma RI / CD64 Background

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

Fc gamma RI / CD64 Synonyms

FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI

Product Reviews

g***t2025-11-29
0People Like
Human Fc gamma RI / CD64 Protein, His Tag (SPR & MALS verified)
Very good product for SPR analyses with antibodies
H***n2023-05-03
0People Like
Mouse Fc gamma RI / CD64 Protein, His Tag (MALS verified)
I used Acro's Fc gamma receptors to build several new antibody binding assays. The proteins arrived promptly, sometimes within a few days of placing the orders. The proteins were also high quality, with no background or issues with stability. I have continued to use them for months with no issues. These produced high quality and robust data with minimal assay development. I would highly recommend this product.