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Fc gamma RIV / CD16-2

Fc gamma RIV / CD16-2 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Mouse (2)
タグ
His Tag (1)His Tag & Avi Tag (1)
マーカー
Unconjugated (1)Biotin-labeled (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
FC4-M52H3	Mouse	HEK293	Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)
FC4-M82E8	Mouse	HEK293	Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag™ (HPLC & BLI verified)

総数量2

Fc gamma RIV / CD16-2バックグランド

FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Cepeprubart	SelK-2	Phase 2 Clinical	Selexys	Venous Thromboembolism; Asthma; Pulmonary Disease, Chronic Obstructive	詳細
Leiolizumab	AbGn 168H2; AbGn-268; AbGn-168H2; ALTB-268	Phase 2 Clinical	Altrubio Inc	Colitis, Ulcerative; Arthritis, Psoriatic	詳細
Neihulizumab	AbGn-168; AbGn-168H; ALTB-168	Phase 1 Clinical	Altrubio Inc	Graft vs Host Disease; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic	詳細
SSGJ-617	SSGJ-617; SSGJ617; 61X; VTX-0811; 617	Phase 1 Clinical	Verseau Therapeutics Inc	Solid tumours	詳細

レビュー

J***y2023-06-24
3評価
Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag™ (HPLC & BLI verified)
I ordered this biotinylated mouse Fc gamma RIV material to test the kinetics of Fc engineered mouse antibodies. The Fc receptor arrived quickly. The certificate of analysis was complete and provided useful recommendations for reconstituting the lyophilized material as well as suggested short and long-term storage conditions. I used the material in Biacore (SPR) using Biotin CAP chip. The material worked well in this assay format and we were able to draw useful conclusions.
1***12019-09-26
1評価
Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)
I have bought a variety of human and mouse Fc receptors from Acro, and the data showned very good stability. In addition, your protein can still produce pretty good data after repeated freeze-thaw cycles in the refrigerator. Love your products!!!