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FGF acidic

FGF acidic 詳細

英語名	Fibroblast growth factor 1	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
研究＆開発段階	Phase 3 Clinical

英語名	Fibroblast growth factor 1
ターゲットの別称	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 3 Clinical

FGF acidic 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
Tag Free (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
AFF-H4116	Human	E. coli	Human FGF acidic Protein, Tag Free

総数量1

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FGF acidicバックグランド

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

FGF acidic分子の別称

FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Muparfostat sodium	PI-88	Phase 3 Clinical	Australian National University	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Prostatic Neoplasms; Skin Melanoma; Solid tumours	詳細
TTHX-1114	TTHX-1114; NM-141; NM141; TTHX1114	Phase 2 Clinical	Florida State University	Corneal Diseases; Corneal Dystrophies, Hereditary; Fuchs' Endothelial Dystrophy; Vascular Diseases	詳細