言語を選択

FGF basic

FGF basic 詳細

英語名	Fibroblast growth factor 2	市販薬剤の数	1
治験薬の数	4	ターゲットの別称	FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2
研究＆開発段階	Approved

英語名	Fibroblast growth factor 2
ターゲットの別称	FGF-2，Heparin-binding growth factor 2，Basic fibroblast growth factor，FGFB，bFGF，HBGF-2，FGF2，Fibroblast Growth Factor 2 (Basic)，Basic Fibroblast Growth Factor BFGF，Prostatropin，Fibroblast Growth Factor 2
市販薬剤の数	1
治験薬の数	4
研究＆開発段階	Approved

FGF basic 製品リスト

属性
Protein (7)Kits (1)
製品ライブラリ
オンライン (8)
種
Human (8)
タグ
Tag Free (6)His Tag & Avi Tag (1)- (1)
マーカー
Unconjugated (6)Biotin-labeled (1)- (1)

製品番号	種	発現システム	製品説明
HOT BFF-H4117	Human	E. coli	Human FGF basic Protein, premium grade
HOT BFF-H5115	Human	E. coli	Human FGF basic (154aa) Protein, premium grade
HOT GMP-FGCH17	Human	E. coli	GMP Human FGF basic Protein
BFF-H4118	Human	E. coli	Human FGF basic Protein, Research Grade
BFF-H5113	Human	E. coli	Human FGF basic Superior Stable Mutant Protein, premium grade
BFF-H5114	Human	E. coli	Human FGF basic Superior Stable Mutant Protein, Research Grade
CEA-C082	Human	-	Human bFGF/FGF2 ELISA Kit
FGC-H81E3	Human	E. coli	Biotinylated Human FGF basic Protein, Avitag™,His Tag (HPLC verified)

総数量8

FGF basicバックグランド

FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. bFGF is a critical component of human embryonic stem cell culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state, although the mechanisms by which it does this are poorly defined. It has been demonstrated to induce gremlin expression which in turn is known to inhibit the induction of differentiation by bone morphogenetic proteins. It is necessary in mouse-feeder cell dependent culture systems, as well as in feeder and serum-free culture systems.

FGF basic分子の別称

FGF2,BFGF,FGFB,FGF basic,HBGF-2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Muparfostat sodium	PI-88	Phase 3 Clinical	Australian National University	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Prostatic Neoplasms; Skin Melanoma; Solid tumours	詳細
RBM-007	ID3 (21); APT-F2; RBM-007	Phase 2 Clinical	Ribomic	Achondroplasia; Macular Degeneration	詳細
Fibroblast growth factor 2 gene therapy (ID Pharma)	SeV-10101; SEV-10101; DVC-10101; BF-30	Phase 2 Clinical	Dnavec	Arterial Occlusive Diseases; Intermittent Claudication; Ischemia; Peripheral Arterial Disease; Peripheral arterial occlusive disorders	詳細
Recombinant Human Epidermal Growth Factor Derivative Gel (Uni-Bio Science)		Phase 1 Clinical	Uni-Bio Science Group	Wounds and Injuries	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Thalidomide	NSC-66847; NSC-527179; K-17; FPF-300; FPF300	Approved	Celgene Corp	Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled	Mainland China	Leprosy, Lepromatous; Multiple Myeloma	Changzhou Pharmaceutical Factory	1982-01-01	Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms	詳細