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Frizzled-10

Frizzled-10 Overview

English Name	Frizzled-10	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	Frizzled Class Receptor 10，FZD10，Frizzled 10， Seven Transmembrane Spanning Receptor，Frizzled Family Receptor 10，HFz10，FzE7，Frizzled (Drosophila) Homolog 10，Frizzled Homolog 10 (Drosophila)，Frizzled Homolog 10，CD350 Antigen，Frizzled-10，CD350，Fz-10，Fz10
Highest Development Stage	Discontinued

English Name	Frizzled-10
Target Synonym	Frizzled Class Receptor 10，FZD10，Frizzled 10， Seven Transmembrane Spanning Receptor，Frizzled Family Receptor 10，HFz10，FzE7，Frizzled (Drosophila) Homolog 10，Frizzled Homolog 10 (Drosophila)，Frizzled Homolog 10，CD350 Antigen，Frizzled-10，CD350，Fz-10，Fz10
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Discontinued

Frizzled-10 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
FRD-H52H3	Human	HEK293	Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified)

Total: 1

Frizzled-10 Background

Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.