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GM-CSF R alpha

GM-CSF R alpha 詳細

英語名	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	市販薬剤の数	0
治験薬の数	4	ターゲットの別称	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
研究＆開発段階	Phase 3 Clinical

英語名	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
ターゲットの別称	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
市販薬剤の数	0
治験薬の数	4
研究＆開発段階	Phase 3 Clinical

GM-CSF R alpha 製品リスト

属性
Protein (3)
製品ライブラリ
オンライン (3)
種
Human (2)Mouse (1)
タグ
His Tag (2)Fc Tag (1)
マーカー
Unconjugated (3)

製品番号	種	発現システム	製品説明
HOT GRA-H52H7	Human	HEK293	Human GM-CSF R alpha Protein, His Tag (SPR verified)
GRA-H5255	Human	HEK293	Human GM-CSF R alpha Protein, Fc Tag
GMA-M52H3	Mouse	HEK293	Mouse GM-CSF R alpha Protein, His Tag

総数量3

GM-CSF R alphaバックグランド

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha分子の別称

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Mavrilimumab	CAM-3001; KPL-301; GM-CSFR; CAM3001	Phase 3 Clinical	Csl Ltd	Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Giant Cell Arteritis; Pneumonia	詳細
Anti-GMR CAR T-cell Therapy		Phase 2 Clinical	Kyoto Prefectural University Of Medicine, Shinshu University School of Medicine	Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Juvenile	詳細
CSF2RA gene-corrected macrophages(University of South Florida)		Phase 2 Clinical	Russian Academy Of Medical Sciences	Pulmonary Alveolar Proteinosis	詳細
STSA-1005	STSA-1005; STSA1005	Phase 1 Clinical	Staidson(Beijing) Biopharmaceuticals Co Ltd	Coronavirus Disease 2019 (COVID-19)	詳細