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GPT

GPT 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
GPT-H51H3	Human	E. coli	Human GPT (1-496) protein, His Tag

総数量1

GPTバックグランド

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Naproxen/Caffeine	BAY-2880376	Phase 3 Clinical	Bayer AG	Pain, Postoperative	詳細
Caffeinol		Phase 3 Clinical	Cardium Therapeutics	Alcoholic Intoxication; Alcoholism; Disruptive, Impulse Control, and Conduct Disorders; Carcinoma, Non-Small-Cell Lung	詳細
Imaradenant	AZD-4635; HTL-1071	Phase 2 Clinical	Nxera Pharma UK Ltd	Solid tumours; Prostatic Neoplasms, Castration-Resistant	詳細
Ciforadenant	CPI-444; V-81444	Phase 2 Clinical	Vernalis (R&D) Ltd	Carcinoma, Renal Cell; Neoplasms; Attention Deficit Disorder with Hyperactivity; Multiple Myeloma; Parkinson Disease; Carcinoma, Non-Small-Cell Lung	詳細
Etrumadenant	AB-928; GS-0928	Phase 2 Clinical	Arcus Biosciences Inc	Prostatic Neoplasms; Melanoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Laryngeal Neoplasms; Mouth Neoplasms; Pharyngeal Neoplasms; Carcinoma, Squamous Cell; Endometrial Neoplasms; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Colorectal Neoplasms; Oropharyngeal Neoplasms; Breast Neoplasms; Head and Neck Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Triple Negative Breast Neoplasms; Hypopharyngeal Neoplasms; Carcinoma, Transitional Cell; Esophageal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Merkel Cell; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Ovarian Neoplasms	詳細
KW-6356	KW-6356	Phase 2 Clinical	Kyowa Hakko Kirin Co Ltd	Parkinson Disease; Hepatic Insufficiency	詳細
PORT-8	PORT-8; TT-53	Phase 2 Clinical	Tarus Therapeutics Inc	Solid tumours	詳細
PORT-6	PORT-6; TT-10	Phase 2 Clinical	Impetis Biosciences Ltd	Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Carcinoma, Non-Small-Cell Lung	詳細
VG081821AC	VG-081821AC; VG081821AC	Phase 2 Clinical	Zhejiang Vimgreen Pharmaceuticals Ltd	Parkinson Disease	詳細
ILB-2109	WTS-001; ILB-2109	Phase 2 Clinical	Hangzhou Wutong Tree Pharmaceutical Co Ltd	Solid tumours; Neoplasms	詳細
PBF-999	PBF-999	Phase 1 Clinical	Palobiofarma Sl	Neoplasms; Huntington Disease	詳細
SHR-5126	SHR-5126	Phase 1 Clinical		Neoplasms	詳細
Taminadenant	NIR-178; PBF-509	Phase 1 Clinical	Palobiofarma Sl	Solid tumours; Ovarian Neoplasms; Head and Neck Neoplasms; Carcinoma, Renal Cell; Carcinoma; Triple Negative Breast Neoplasms; Lymphoma, Large B-Cell, Diffuse; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Colorectal Neoplasms; Parkinson Disease; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Melanoma	詳細
ST-4206	ST-4206	Phase 1 Clinical	Alfasigma Spa	Parkinson Disease	詳細
JNJ-86974680	JNJ-86974680	Phase 1 Clinical	Johnson & Johnson Enterprise Innovation Inc	Carcinoma, Non-Small-Cell Lung	詳細
YZJ-5053	YZJ5053; YZJ-5053	Phase 1 Clinical	Shanghai Haiyan Pharmaceutical Technology Co Ltd	Solid tumours; Neoplasm Metastasis	詳細
CT-1500	CT-1500	Phase 1 Clinical	Circadian Technologies Ltd		詳細
DZD-2269		Phase 1 Clinical	Dizal Pharmaceutical Co Ltd	Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms	詳細
INCB-106385	INCB-106385	Phase 1 Clinical	Incyte Corp	Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular	詳細
CS-3005	CS-3005	Phase 1 Clinical	Cstone Pharmaceuticals (Suzhou) Co Ltd	Solid tumours	詳細
Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine/Mannitol/Sodium Chloride					詳細
Sodium Citrate/Citric Acid/Dextrose					詳細
Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine					詳細
Aspirin/Acetaminophen/Caffeine/Thiamine					詳細
Propranolol hydrochloride/Caffeine/Phenytoin Sodium					詳細
Ethenzamide/Caffeine/Chlorzoxazone					詳細
Salicylamide/Acetaminophen/Caffeine					詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Regadenoson Hydrate	CVT-3146	Approved	Astellas Pharma Inc	Lexiscan, Rapiscan	United States	Contrast agents	Astellas Pharma Inc	2008-04-10	Myocardial Ischemia; Rejection of lung transplantation; Cardiovascular contrast agents; Pneumonia; Glioblastoma; Coronary Artery Disease; Retinal Artery Occlusion; Heart Diseases; Coronavirus Disease 2019 (COVID-19); Oligodendroglioma; Contrast agents; Astrocytoma; Cardiovascular Diseases; Glioma; Diagnostic agents; Anemia, Sickle Cell	詳細
Caffeine/Ergotamine Tartrate		Approved	Novartis Pharma Ag	Cafergot	Mainland China	Migraine Disorders	Tianjin Medical University Pharmaceutical Factory	1948-11-26	Migraine Disorders	詳細
Oxtriphylline		Approved		Theocolin	Canada		null		Asthma	詳細
Caffeine/Metamizole Sodium/Dihydroergotamine Mesylate		Approved		Cefaliv					Migraine Disorders	詳細
Adenine		Approved		Leucon	Japan	Leukopenia	Ohara Pharmaceutical Co Ltd		Leukemia; Leukopenia	詳細
Istradefylline	KW-6002	Approved	Kyowa Hakko Kirin Co Ltd	Nourianz, Nouriast	Japan	Parkinson Disease	Kyowa Hakko Kirin Co Ltd	2013-03-25	Substance-Related Disorders; Restless Legs Syndrome; Sleep Wake Disorders; Parkinson Disease; Hepatic Insufficiency; Movement Disorders; Cognition Disorders; Amyotrophic Lateral Sclerosis	詳細
Acetaminophen/Methylephedrine Hydrochloride/Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Caffeine/Sulfogaiacol		Approved			Mainland China	Common Cold	Zhejiang Apeloa Kangyu Pharmaceutical Co Ltd		Common Cold	詳細
Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Sodium Citrate/Ammonium Chloride/Caffeine		Approved		尔可芬					Cough	詳細
Acetaminophen/Caffeine/Codeine Phosphate/Diphenhydramine Hydrochloride		Approved		斯力帮					Headache	詳細
Ferric Ammonium Citrate/Vitamin B1/Sodium glycerophosphate/Caffeine		Approved							Ischemia	詳細
Norethidranum Dipropionas/Caffeine/Vitamin B6		Approved			Mainland China	Contraception	Huazhong Pharmaceutical Co Ltd	1981-01-01	Contraception	詳細
Acetaminophen/Propyphenazone/Caffeine		Approved		散利痛, 散列通					Common Cold	詳細
Quinine Hydrochloride Hydrate/Caffeine		Approved							Malaria	詳細
Dihydroergocryptine/Caffeine		Approved		洛斯宝, VASOBRAL					Diabetic Retinopathy; Diabetes Mellitus	詳細
Aminophenazone/Phenacetin/Caffeine		Approved							Pain; Fever	詳細
Aminophenazone/Caffeine/Calcium Glycerophosphate		Approved							Headache; Dysmenorrhea; Neuralgia	詳細
Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aminophenazone/Caffeine/Chlorphenamine Maleate		Approved							Headache; Common Cold; Neuralgia	詳細
Aspirin/Caffeine/Codeine Phosphate		Approved		柯克					Pain	詳細
Acetaminophen/Pseudoephedrine Hydrochloride/Caffeine		Approved							Common Cold	詳細
Aspirin/Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aspirin/Caffeine/Chlorphenamine Maleate/Tartaric Acid		Approved							Common Cold	詳細
Acetaminophen/Caffeine/Pseudoephedrine Hydrochloride/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aminophenazone/Phenacetin/Caffeine/Phenobarbital		Approved							Migraine Disorders	詳細
Acetaminophen/Chlorphenamine Maleate/Caffeine/Guaifenesin		Approved							Common Cold	詳細
Acetaminophen/Amantadine Hydrochloride/Caffeine/Artificial Bezoar		Approved							Common Cold	詳細
Acetaminophen/Salicylamide/Pseudoephedrine Hydrochloride/Caffeine/Triprolidine Hydrochloride Hydrate		Approved		联邦菲迪乐					Common Cold	詳細
Sodium Benzoate/Caffeine		Approved							Central Nervous System Diseases	詳細
Aminophenazone/Caffeine		Approved							Fever	詳細
Antipyrine/Caffeine		Approved							Common Cold	詳細
Aspirin/Caffeine		Approved							Common Cold	詳細
Antipyrine/Caffeine/Citric Acid		Approved		米格来宁	Mainland China	Sedation	Xi'An Disai Biological Pharmaceutical Co Ltd, Heilongjiang Hasing Pharmaceutical Group Co Ltd, Huadong Medicine (Xi'An) Bodyguard Pharmaceutical Co Ltd, Mudanjiang Lingtai Medicdment Co Ltd	1982-01-01	Sedation	詳細
Aminophenazone/Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved		克感敏, 扑感敏, 朴感敏					Common Cold	詳細
Acetaminophen/Caffeine/Ephedrine Hydrochloride/Diphenhydramine Hydrochloride		Approved							Influenza, Human	詳細
Acetaminophen/Caffeine/Chlorphenamine Maleate/Artificial Bezoar		Approved							Common Cold	詳細
Aspirin/Phenacetin/Caffeine		Approved							Headache; Dysmenorrhea; Toothache; Neuralgia; Fever; Arthralgia	詳細
Aspirin/Caffeine/Acetaminophen		Approved			United States	Migraine Disorders	Haleon PLC		Migraine Disorders; Anesthesia	詳細
Acetaminophen/Butalbital/Caffeine		Approved							Headache	詳細
Acetaminophen/Caffeine		Approved	Zentiva As		Mainland China	Pain	Sino--American Shanghai Squibb Pharmaceutical Ltd		Pain	詳細
Sodium glycerophosphate/Caffeine/Vitamin B/Phosphoric Acid/Niacin		Approved								詳細
Acetaminophen/Caffeine/Phenylephrine Hydrochloride/Chlorphenamine Maleate/Vitamin B		Approved								詳細
Acetaminophen/Chlorphenamine Maleate/Methylephedrine Hydrochloride/Sulfogaiacol/Caffeine		Approved			Mainland China	Common Cold	Hainan Sanfengyou Pharmaceutical Co Ltd	2006-05-16	Common Cold	詳細
Brompheniramine Maleate/Bromhexine Hydrochloride/Caffeine/Acetaminophen/Phenylephrine Hydrochloride		Approved							Common Cold	詳細
Acetaminophen/Amantadine Hydrochloride/Caffeine/Chlorphenamine Maleate/Artificial Bezoar		Approved		复方氨酚烷胺	Mainland China	Common Cold	null	1984-01-01	Common Cold	詳細
Caffeine		Approved							Fatigue; Mental Fatigue; Memory Disorders; Cocaine-Related Disorders; Sexual Dysfunction, Physiological; Parkinson Disease; Cognitive Dysfunction; Diabetes Complications; Diabetic Nephropathies; Postoperative Cognitive Complications; Diabetes Mellitus, Type 1; Delirium; Apnea; Disorders of Excessive Somnolence; Intermittent Claudication; Spinal Cord Injuries; Fetal Membranes, Premature Rupture; Consciousness; Sleepiness	詳細