HABP1

HABP1

HABP1 詳細

Molecule Name
HLA-DR antigens-associated invariant chain
分子の別称
C1QBP,GC1QBP,HABP1,SF2P32,p33
Drug Development Progress
治験薬の数4
市販薬剤の数0
研究&開発段階Phase 2 Clinical
ターゲットの別称
CLIP,CD74,Ia antigen-associated invariant chain,CD74 Molecule,CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated),CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain,HLA-DR Antigens-Associated Invariant Chain,Ia-Associated Invariant Chain,MHC HLA-DR Gamma Chain,HLA-DR-Gamma,DHLAG,P33,CD74 Antigen,Ia-GAMMA,HLADG,II,Gamma Chain Of Class II Antigens,HLA Class II Histocompatibility Antigen Gamma Chain
バックグランド
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP), a member of the MAM33 family, is also known as ASF/SF2-associated protein p32, glycoprotein gC1qBP (C1qBP), mitochondrial matrix protein p32 and hyaluronan-binding protein 1, which is a homotrimer that contains three monomers forming a donut-shaped structure with an unusually asymmetric charge distribution on the surface. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. C1QBP has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. Furthermore, C1QBP has been shown to interact with Protein kinase D1, BAT2, PRKCD, PKC alpha and Protein kinase Mζ .

HABP1 製品リスト

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治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
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詳細