HLA-A*2402 & B2M & WT-1 (CYTWNQMNL)

Wilms tumor gene 1 (WT1)，is an attractive target antigen for leukemia and solid cancer. WT1-specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The human HLA-A*2402 WT-1 (CYTWNQMNL) complex protein is a complex of HLA-A*2402 of the MHC Class I, B2M and CYTWNQMNL peptide of the WT-1.