IFN-beta

IFN-beta

IFN-beta 詳細

Molecule Name
Interferon beta
分子の別称
IFNB1,Interferon beta,IFN-beta,IFB,IFNB
Drug Development Progress
治験薬の数6
市販薬剤の数1
研究&開発段階Approved
ターゲットの別称
Interferon Beta 1,Interferon, Beta 1, Fibroblast,IFNB,IFB,IFF,Interferon-beta,IFN-beta,Fibroblast interferon,IFNB1,Interferon beta
バックグランド
Interferon beta(IFN beta) is type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity)

IFN-beta 製品リスト

Species
  • Human(2)
  • Mouse(1)
Tag
  • His Tag & Avi Tag(2)
  • Fc Tag(1)
Host
  • HEK293(3)
Conjugate
  • Biotin-labeled(2)
  • Unconjugated(1)
Grade
  • RUO(3)
Low Endotoxin
  • No(3)
MoleculeCat. No.Product Name種HostStructurePurityActivitySize&Price
IFN-beta
Human IFN-beta Protein, Fc Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$350.00

100ug
IFN-beta
Avitag
IFB-H82E4
Biotinylated Human IFN-beta Protein, His,Avitag™ (MALS & SPR verified)
Human
HEK293
MALSSDS-PAGE
SPR

$360.00

25ug
IFN-beta
Avitag
IFB-M82E3
Biotinylated Mouse IFN-beta Protein, His,Avitag™ (MALS & SPR verified)
Mouse
HEK293
MALSSDS-PAGE
SPR

$360.00

25ug
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治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
DazukibartPF-06823859Phase 3 ClinicalPfizer Inc
Dermatomyositis; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Muscular Diseases; Myositis; Polymyositis
詳細
Peginterferon beta-1a (CinnaGen)Phase 3 ClinicalCinnagen
Multiple Sclerosis, Relapsing-Remitting
詳細
VSV-IFNbeta-NISPhase 2 ClinicalVyriad
Angioimmunoblastic T-cell Lymphoma; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Endometrial Neoplasms; Histiocytoma; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Myeloma; Mycosis Fungoides; Myelodysplastic Syndromes; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck
詳細
VSV-hIFNbeta-NIS (University of Tennessee)Phase 1 ClinicalThe University Of Tennessee
Endometrial Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Multiple Myeloma
詳細
MEM-288MEM-288Phase 1 ClinicalMemgen
Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Melanoma; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms
詳細
SCD-153SCD-153Phase 1 ClinicalInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Johns Hopkins University, Sun Pharma Advanced Research Company Ltd
Alopecia Areata
詳細

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
PropagermaniumSK-818; SK-818CApprovedSanwa Kagaku Kenkyusho Co LtdSerocionJapanHepatitis BSanwa Kagaku Kenkyusho Co Ltd1994-01-01
Hepatitis B
詳細
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