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IFN-beta

IFN-beta 詳細

英語名	Interferon beta	市販薬剤の数	1
治験薬の数	6	ターゲットの別称	Interferon Beta 1，Interferon， Beta 1， Fibroblast，IFNB，IFB，IFF，Interferon-beta，IFN-beta，Fibroblast interferon，IFNB1，Interferon beta
研究＆開発段階	Approved

英語名	Interferon beta
ターゲットの別称	Interferon Beta 1，Interferon， Beta 1， Fibroblast，IFNB，IFB，IFF，Interferon-beta，IFN-beta，Fibroblast interferon，IFNB1，Interferon beta
市販薬剤の数	1
治験薬の数	6
研究＆開発段階	Approved

IFN-beta 製品リスト

属性
Protein (3)
製品ライブラリ
オンライン (3)
種
Human (2)Mouse (1)
タグ
Fc Tag (1)His Tag & Avi Tag (2)
マーカー
Unconjugated (1)Biotin-labeled (2)

製品番号	種	発現システム	製品説明
IFB-H5254	Human	HEK293	Human IFN-beta Protein, Fc Tag (MALS verified)
IFB-H82E4	Human	HEK293	Biotinylated Human IFN-beta Protein, His,Avitag™ (MALS & SPR verified)
IFB-M82E3	Mouse	HEK293	Biotinylated Mouse IFN-beta Protein, His,Avitag™ (MALS & SPR verified)

総数量3

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IFN-betaバックグランド

Interferon beta(IFN beta) is type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity)

IFN-beta分子の別称

IFNB1,Interferon beta,IFN-beta,IFB,IFNB

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Dazukibart	PF-06823859	Phase 3 Clinical	Pfizer Inc	Dermatomyositis; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Muscular Diseases; Myositis; Polymyositis	詳細
Peginterferon beta-1a (CinnaGen)		Phase 3 Clinical	Cinnagen	Multiple Sclerosis, Relapsing-Remitting	詳細
VSV-IFNbeta-NIS		Phase 2 Clinical	Vyriad	Angioimmunoblastic T-cell Lymphoma; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Endometrial Neoplasms; Histiocytoma; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Myeloma; Mycosis Fungoides; Myelodysplastic Syndromes; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck	詳細
VSV-hIFNbeta-NIS (University of Tennessee)		Phase 1 Clinical	The University Of Tennessee	Endometrial Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Multiple Myeloma	詳細
MEM-288	MEM-288	Phase 1 Clinical	Memgen	Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Melanoma; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	詳細
SCD-153	SCD-153	Phase 1 Clinical	Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Johns Hopkins University, Sun Pharma Advanced Research Company Ltd	Alopecia Areata	詳細