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IL-1 RAcP

IL-1 RAcP 詳細

英語名	Interleukin-1 receptor accessory protein	市販薬剤の数	0
治験薬の数	8	ターゲットの別称	Interleukin-1 receptor 3，IL-1RAcP，IL-1 receptor accessory protein，IL-1R-3，C3orf13，Interleukin 1 Receptor Accessory Protein，IL1R3，Interleukin-1 Receptor Accessory Protein Beta，IL-1R3
研究＆開発段階	Phase 2 Clinical

英語名	Interleukin-1 receptor accessory protein
ターゲットの別称	Interleukin-1 receptor 3，IL-1RAcP，IL-1 receptor accessory protein，IL-1R-3，C3orf13，Interleukin 1 Receptor Accessory Protein，IL1R3，Interleukin-1 Receptor Accessory Protein Beta，IL-1R3
市販薬剤の数	0
治験薬の数	8
研究＆開発段階	Phase 2 Clinical

IL-1 RAcP 製品リスト

属性
Protein (11)Cell (1)
製品ライブラリ
オンライン (12)
種
Human (8)Mouse (1)Cynomolgus (1)Rat (1)Porcine (1)
タグ
His Tag (8)Fc Tag (1)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)- (1)
マーカー
Unconjugated (7)Biotin-labeled (2)FITC Labeled (1)PE Labeled (1)- (1)

製品番号	種	発現システム	製品説明
HOT ILP-H5225	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, His Tag (MALS verified)
HOT ILP-H5256	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag
HOT ILP-H82E5	Human	HEK293	Biotinylated Human IL-1 RAcP / IL-1 R3 Protein, His,Avitag™ (MALS verified)
HOT ILP-M52H5	Mouse	HEK293	Mouse IL-1 RAcP / IL-1 R3 Protein, His Tag
HOT ILP-C52H5	Cynomolgus	HEK293	Cynomolgus IL-1 RAcP / IL-1 R3 Protein, His Tag
CCHO-ATP257	Human	CHO	CHO/Human IL-1 RAcP Stable Cell Line
ILP-H52H4	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, His Tag, low endotoxin (MALS verified)
ILP-H82F5	Human	HEK293	Biotinylated Human IL-1 RAcP / IL-1 R3 Protein, Fc,Avitag™ (MALS verified)
ILP-HF223	Human	HEK293	FITC-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag
ILP-HP2H3	Human	HEK293	PE-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag (Site-specific conjugation)

総数量12

IL-1 RAcPバックグランド

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

IL-1 RAcP分子の別称

IL1RAP,IL-1RAcP,C3orf13,IL1R3

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Nidanilimab	CAN-04	Phase 2 Clinical	Lund University Foundation	Biliary Tract Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Transitional Cell; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Pancreatic Neoplasms; Sarcoidosis, Pulmonary; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms	詳細
CCTx-001	CCTx-001	Phase 2 Clinical	Advesya SAS	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	詳細
SAR-445399	SAR-445399	Phase 2 Clinical	Sanofi	Hidradenitis Suppurativa; Immune System Diseases; Inflammation	詳細
IBI-3011	IBI-3011; IBI3011	Phase 1 Clinical		Arthritis, Gouty; Gout	詳細
Gene modified anti-IL1RAP Chimeric Antigen Receptor T Cells therapy(Shanghai Zhongshan Hospital)		Phase 1 Clinical	Shanghai Zhongshan Hospital	Carcinoma, Hepatocellular	詳細
AK-135	AK135; AK-135	Phase 1 Clinical		Peripheral Nervous System Diseases	詳細
DXP-106	DXP-106; DXP106	Phase 1 Clinical	Singlomics Biopharmaceuticals Co Ltd	Neoplasms; Solid tumours	詳細
GSK-3903371	GSK-3903371; BOS-371	Clinical	Glaxosmithkline Plc	Neoplasms	詳細