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ホームページすべての分子IL-11 R alpha
IL-11 R alpha
IL-11 R alpha 詳細
| 英語名 | Interleukin 11 receptor alpha | 市販薬剤の数 | 9 |
| 治験薬の数 | 3 | ターゲットの別称 | Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA |
| 研究＆開発段階 | Approved | ||
| 英語名 | Interleukin 11 receptor alpha |
| ターゲットの別称 | Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA |
| 市販薬剤の数 | 9 |
| 治験薬の数 | 3 |
| 研究＆開発段階 | Approved |
IL-11 R alpha 製品リスト
- 属性
Protein (6)Cell (1)
- 製品ライブラリ
オンライン (7)
- 種
Human (4)Mouse (2)Rhesus macaque (1)
- タグ
Fc Tag (1)Fc Tag & Avi Tag (1)His Tag (2)- (1)Avi Tag (1)His Tag & Avi Tag (1)
- マーカー
Unconjugated (3)Biotin-labeled (3)- (1)
| 製品番号 | 種 | 発現システム | 製品説明 | タンパク質の構造 | 純度 | 特性 |
|---|---|---|---|---|---|---|
HOT CHEK-ATF052 |  Human | HEK293 | Human IL-11 R alpha (Luc) HEK293 Reporter Cell |  | ||
HOT ILR-H5256 | Human | HEK293 | Human IL-11 R alpha Protein, Fc Tag (MALS verified) |  |  |  |
HOT ILR-H52H5 | Human | HEK293 | Human IL-11 R alpha Protein, His Tag, low endotoxin (MALS & BLI verified) |  | | |
HOT ILR-H82F5 | Human | HEK293 | Biotinylated Human IL-11 R alpha Protein, Fc,Avitag™ (MALS verified) |  | | |
HOT ILR-M52H9 |  Mouse | HEK293 | Mouse IL-11 R alpha Protein, His Tag |  | | |
| Mouse | HEK293 | Biotinylated Mouse IL-11 R alpha Protein, Avitag™ |  | | | |
 Rhesus macaque | HEK293 | Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag™ (MALS verified) |  | | |
総数量7
- 1
IL-11 R alphaバックグランド
Interleukin-11 receptor subunit alpha (IL-11RA) is a type I transmembrane hematopoietic cytokine receptor serving as the ligand-specific binding subunit for IL-11. It harbors an extracellular cytokine-binding homology region, binds IL-11 with low affinity on its own, and recruits the shared, ubiquitously expressed signal-transducing coreceptor gp130 to assemble a functional high-affinity hexameric signaling complex upon ligand engagement. Widely expressed on stromal, epithelial and hematopoietic cells, IL-11RA mediates activation of JAK/STAT (predominantly STAT3), MAPK and PI3K pathways, governing critical biological processes including hematopoiesis, tissue damage repair and immune homeostasis, and is closely linked to fibrotic disorders and tumor progression.
IL-11 R alpha分子の別称
IL-11 R alpha,IL-11 RA,IL11RA,Interleukin-11 receptor subunit alpha,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha
治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| Δ1-9, alanine 10, asparagine 134, recombinant human interleukin-11 | Phase 3 Clinical | Fuzhou Quanye Economic Technology Co Ltd | Thrombocytopenia | 詳細 | |
| LASN-01 | LASN-01 | Phase 2 Clinical | Csl Ltd | Endocrine System Diseases; Exophthalmos; Eye Diseases; Graves Ophthalmopathy; Pulmonary Fibrosis | 詳細 |
| NMX-1 | NMX-1 | Phase 2 Clinical | Novomedix LLC | Triple Negative Breast Neoplasms | 詳細 |
市販薬剤に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | オリジナル製品名 | 最初に承認をした国 | 最初の適応症 | 最初に承認を受けた会社 | 承認された日付 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|---|---|---|---|---|
| Oprelvekin biosimilar (Hangzhou Jiuyuan Gene Engineering) | Approved | Hangzhou Jiuyuan Gene Biomedical Co Ltd | 吉巨芬, Jijufen | Mainland China | Thrombocytopenia | Hangzhou Jiuyuan Gene Biomedical Co Ltd | 2003-09-18 | Thrombocytopenia | 詳細 | |
| Recombinant human interleukin-11 (Qilu Pharmaceutical) | Approved | Qilu Pharmaceutical Co Ltd | 巨和粒 | Mainland China | Thrombocytopenia | Qilu Pharmaceutical Co Ltd | 2003-03-18 | Thrombocytopenia | 詳細 | |
| Recombinant human interleukin-11 (Kerun Biopharmaceutical) | Approved | Chongqing Kerun Biologic Pharmaceutical Development Co Ltd | 百杰依 | Mainland China | Thrombocytopenia | China Resources Angde Biotech Pharma Co Ltd | 2008-05-08 | Thrombocytopenia | 詳細 | |
| Recombinant human interleukin-11 (Beijing ShuangLu Pharmaceutical) | Approved | Beijing Sl Pharmaceutical Co Ltd | 迈格尔 | Mainland China | Thrombocytopenia | Beijing Sl Pharmaceutical Co Ltd | 2003-03-17 | Thrombocytopenia | 詳細 | |
| Recombinant human interleukin-11 (Xiamen Amoytop Biotech) | rHuIL-11 | Approved | Xiamen Amoytop Biotech Co Ltd | 特尔康 | Mainland China | Thrombocytopenia | Xiamen Amoytop Biotech Co Ltd | 2005-04-11 | Thrombocytopenia | 詳細 |
| Recombinant human interleukin 11 (BioGeneric Pharma) | Approved | Biogeneic Pharma | Thrombocytopenia | 詳細 | ||||||
| Recombinant human interleukin-11 for injection | Approved | 詳細 | ||||||||
| Recombinant human interleukin-11 (Shanghai CP Guojian) | Approved | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | 欣美格 | Mainland China | Thrombocytopenia | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | 2005-04-26 | Thrombocytopenia | 詳細 | |
| Recombinant human interleukin-11 (Diao group) | Approved | Chengdu Diao Jiuhong Pharmaceutical Factory | 依星 | Mainland China | Thrombocytopenia | Chengdu Diao Jiuhong Pharmaceutical Factory | 2003-04-23 | Thrombocytopenia | 詳細 |
- 詳細
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- 市販薬剤に関する情報
- 治験薬に関する情報
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