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IL-11 R alpha

IL-11 R alpha 詳細

英語名	Interleukin 11 receptor alpha	市販薬剤の数	9
治験薬の数	3	ターゲットの別称	Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA
研究＆開発段階	Approved

英語名	Interleukin 11 receptor alpha
ターゲットの別称	Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA
市販薬剤の数	9
治験薬の数	3
研究＆開発段階	Approved

IL-11 R alpha 製品リスト

属性
Protein (5)Cell (1)
製品ライブラリ
オンライン (6)
種
Human (4)Mouse (2)
タグ
Fc Tag (1)Fc Tag & Avi Tag (1)His Tag (2)- (1)Avi Tag (1)
マーカー
Unconjugated (3)Biotin-labeled (2)- (1)

製品番号	種	発現システム	製品説明
HOT CHEK-ATF052	Human	HEK293	Human IL-11 R alpha (Luc) HEK293 Reporter Cell
HOT ILR-H5256	Human	HEK293	Human IL-11 R alpha Protein, Fc Tag (MALS verified)
HOT ILR-H52H5	Human	HEK293	Human IL-11 R alpha Protein, His Tag, low endotoxin (MALS verified)
HOT ILR-H82F5	Human	HEK293	Biotinylated Human IL-11 R alpha Protein, Fc,Avitag™ (MALS verified)
HOT ILR-M52H9	Mouse	HEK293	Mouse IL-11 R alpha Protein, His Tag
ILR-M82E8	Mouse	HEK293	Biotinylated Mouse IL-11 R alpha Protein, Avitag™

総数量6

IL-11 R alphaバックグランド

Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.

IL-11 R alpha分子の別称

IL-11 R alpha,IL-11 RA,IL11RA,Interleukin-11 receptor subunit alpha,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Δ1-9, alanine 10, asparagine 134, recombinant human interleukin-11		Phase 3 Clinical	Fuzhou Quanye Economic Technology Co Ltd	Thrombocytopenia	詳細
LASN-01	LASN-01	Phase 2 Clinical	Csl Ltd	Endocrine System Diseases; Exophthalmos; Eye Diseases; Graves Ophthalmopathy; Pulmonary Fibrosis	詳細
NMX-1	NMX-1	Phase 2 Clinical	Novomedix LLC	Triple Negative Breast Neoplasms	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Oprelvekin biosimilar (Hangzhou Jiuyuan Gene Engineering)		Approved	Hangzhou Jiuyuan Gene Biomedical Co Ltd	吉巨芬, Jijufen	Mainland China	Thrombocytopenia	Hangzhou Jiuyuan Gene Biomedical Co Ltd	2003-09-18	Thrombocytopenia	詳細
Recombinant human interleukin-11 (Qilu Pharmaceutical)		Approved	Qilu Pharmaceutical Co Ltd	巨和粒	Mainland China	Thrombocytopenia	Qilu Pharmaceutical Co Ltd	2003-03-18	Thrombocytopenia	詳細
Recombinant human interleukin-11 (Kerun Biopharmaceutical)		Approved	Chongqing Kerun Biologic Pharmaceutical Development Co Ltd	百杰依	Mainland China	Thrombocytopenia	China Resources Angde Biotech Pharma Co Ltd	2008-05-08	Thrombocytopenia	詳細
Recombinant human interleukin-11 (Beijing ShuangLu Pharmaceutical)		Approved	Beijing Sl Pharmaceutical Co Ltd	迈格尔	Mainland China	Thrombocytopenia	Beijing Sl Pharmaceutical Co Ltd	2003-03-17	Thrombocytopenia	詳細
Recombinant human interleukin-11 (Xiamen Amoytop Biotech)	rHuIL-11	Approved	Xiamen Amoytop Biotech Co Ltd	特尔康	Mainland China	Thrombocytopenia	Xiamen Amoytop Biotech Co Ltd	2005-04-11	Thrombocytopenia	詳細
Recombinant human interleukin 11 (BioGeneric Pharma)		Approved	Biogeneic Pharma						Thrombocytopenia	詳細
Recombinant human interleukin-11 for injection		Approved								詳細
Recombinant human interleukin-11 (Shanghai CP Guojian)		Approved	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	欣美格	Mainland China	Thrombocytopenia	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	2005-04-26	Thrombocytopenia	詳細
Recombinant human interleukin-11 (Diao group)		Approved	Chengdu Diao Jiuhong Pharmaceutical Factory	依星	Mainland China	Thrombocytopenia	Chengdu Diao Jiuhong Pharmaceutical Factory	2003-04-23	Thrombocytopenia	詳細