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IL-22 R alpha 1

IL-22 R alpha 1 詳細

英語名	Interleukin-22 receptor	市販薬剤の数	0
治験薬の数	5	ターゲットの別称
研究＆開発段階	Phase 2 Clinical

英語名	Interleukin-22 receptor
ターゲットの別称
市販薬剤の数	0
治験薬の数	5
研究＆開発段階	Phase 2 Clinical

IL-22 R alpha 1 製品リスト

属性
Protein (5)
製品ライブラリ
オンライン (5)
種
Mouse (1)Cynomolgus (1)Human (3)
タグ
His Tag (3)Fc Tag (1)His Tag & Avi Tag (1)
マーカー
Unconjugated (4)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
IL1-H5257	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, Fc Tag (MALS verified)
IL1-H52H7	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, His Tag (MALS & SPR verified)
IL1-H82E5	Human	HEK293	Biotinylated Human IL-22 R alpha 1 Superstable Mutant Protein, His,Avitag™ (HPLC verified)
IL1-M52H8	Mouse	HEK293	Mouse IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)
IL1-C52H7	Cynomolgus	HEK293	Cynomolgus IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)

総数量5

IL-22 R alpha 1バックグランド

Interleukin-22 receptor subunit alpha-1(IL22RA1) is a component of the receptor for IL20, IL22 and IL24.Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Efmarodocokin alfa	RO-7021610; UTTR-1147A; RG-7880	Phase 2 Clinical	Genentech Inc	Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Diabetic Foot; Graft vs Host Disease	詳細
Temtokibart	ARGX-112; LEO-138559; LP-0145	Phase 2 Clinical	Argenx Se, Leo Pharma Inc	Dermatitis, Atopic	詳細
CK-0045	CK-0045	Phase 2 Clinical	Cytoki Pharma ApS	Diabetes Mellitus, Type 2; Obesity; Overweight	詳細
Eflepedocokin alfa	F-652	Phase 2 Clinical	Evive Biotech Ltd	Acute-On-Chronic Liver Failure; Coronavirus Disease 2019 (COVID-19); Enteritis; Enterocolitis, Necrotizing; Graft vs Host Disease; Hepatitis, Alcoholic; Pancreatitis	詳細
ABBV-022	ABBV-022	Phase 1 Clinical	Abbvie Inc	Colitis, Ulcerative	詳細