IL-24

IL-24 詳細

英語名Interleukin 24市販薬剤の数0
治験薬の数1ターゲットの別称ST16,Interleukin-24,IL24,MDA-7,Suppression of tumorigenicity 16 protein,IL-24,Interleukin 24,Suppression Of Tumorigenicity 16 (Melanoma Differentiation),Melanoma Differentiation-Associated Gene 7 Protein,IL-4-Induced Secreted Protein,MDA7,Melanoma Differentiation Association Protein 7,Melanocyte-Associated Mda-7,IL10B,C49A,FISP,MOB5,Mob-5
研究&開発段階Phase 1 Clinical
英語名Interleukin 24
ターゲットの別称ST16,Interleukin-24,IL24,MDA-7,Suppression of tumorigenicity 16 protein,IL-24,Interleukin 24,Suppression Of Tumorigenicity 16 (Melanoma Differentiation),Melanoma Differentiation-Associated Gene 7 Protein,IL-4-Induced Secreted Protein,MDA7,Melanoma Differentiation Association Protein 7,Melanocyte-Associated Mda-7,IL10B,C49A,FISP,MOB5,Mob-5
市販薬剤の数0
治験薬の数1
研究&開発段階Phase 1 Clinical

IL-24 製品リスト

  • 属性

    Protein (1)

  • 製品ライブラリ

    オンライン (1)

  • Human (1)

  • タグ

    His Tag (1)

  • マーカー

    Unconjugated (1)

製品番号発現システム製品説明タンパク質の構造純度特性
IL4-H52H4
Human
HEK293
Human IL-24 Protein, His Tag (BLI verified)
総数量1
  • 1

IL-24バックグランド

Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.

IL-24分子の別称

Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
Interleukin 24 gene therapy (MultiVir)Ad-IL-24; Ad-IL24Phase 1 ClinicalMultivir IncHead and Neck Neoplasms; Melanoma
詳細
  • 詳細
  • 製品リスト
  • 治験薬に関する情報
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