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IL-4

IL-4 詳細

英語名	Interleukin-4	市販薬剤の数	2
治験薬の数	14	ターゲットの別称	MGC79402，B-cell stimulatory factor 1，Lymphocyte stimulatory factor 1，IL4，Interleukin 4，B_cell Stimulatory Factor 1，B Cell Growth Factor 1，Binetrakin，Pitrakinra，BSF-1，IL-4，Interleukin 4 Variant 2，BCGF-1，BCGF1，BSF1，Interleukin-4
研究＆開発段階	Approved

英語名	Interleukin-4
ターゲットの別称	MGC79402，B-cell stimulatory factor 1，Lymphocyte stimulatory factor 1，IL4，Interleukin 4，B_cell Stimulatory Factor 1，B Cell Growth Factor 1，Binetrakin，Pitrakinra，BSF-1，IL-4，Interleukin 4 Variant 2，BCGF-1，BCGF1，BSF1，Interleukin-4
市販薬剤の数	2
治験薬の数	14
研究＆開発段階	Approved

IL-4 製品リスト

属性
Protein (12)Kits (5)
製品ライブラリ
オンライン (15)研究中 (2)
種
Human (10)Mouse (3)Cynomolgus (3)Rabbit (1)
タグ
Tag Free (3)His Tag & Avi Tag (3)His Tag (4)Fc Tag (2)- (5)
マーカー
Unconjugated (9)Biotin-labeled (3)- (5)

製品番号	種	発現システム	製品説明
HOT GMP-L04H26	Human	HEK293	GMP Human IL-4 Protein
HOT IL4-H4218	Human	HEK293	Human IL-4 Protein, premium grade
HOT IL4-H5253	Human	HEK293	Human IL-4 Protein, Fc Tag, low endotoxin (MALS verified)
HOT IL4-H52H9	Human	HEK293	Human IL-4 Protein, His Tag, low endotoxin (MALS verified)
HOT IL4-H82E0	Human	HEK293	Biotinylated Human IL-4 Protein, Avitag™,His Tag (MALS verified)
CRS-A004	Human	-	resDetect™ Human Interleukin-4 (IL-4) ELISA Kit (Residue Testing)
CRS-B003	Human	-	Human IL-4 ELISA Kit
EP-132	Human	-	IL-4 [Biotinylated] : IL-4Rα Inhibitor Screening ELISA Kit
FCSh-002	Human	-	Human IL-4 Detection Kit (Flow Cytometry Bead Assay)
IL4-H5219	Human	HEK293	Human IL-4 Protein, Research Grade

総数量17

IL-4バックグランド

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

IL-4分子の別称

IL4,BCGF1,BSF1

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Dupilumab biosimilar (Jingxing Pharmaceutical)	GS101; GS-101; GS-101 (Jingxing Pharmaceutical)	Phase 3 Clinical	Jiangsu Jingxing Pharmaceutical Technology Co Ltd	Dermatitis, Atopic	詳細
Dupilumab biosimilar (Qilu Pharma)	QL2108; QL-2108	Phase 3 Clinical	Qilu Pharmaceutical Co Ltd	Asthma; Dermatitis, Atopic; Prurigo	詳細
Tilrekimig	PF-07275315	Phase 3 Clinical	Pfizer Inc	Asthma; Dermatitis, Atopic; Pulmonary Disease, Chronic Obstructive	詳細
Eblasakimab	MK-6105; ASLAN-004; CSL-334	Phase 2 Clinical	Csl Ltd, Merck Sharp & Dohme Corp	Dermatitis, Atopic; Hypersensitivity	詳細
Dectrekumab/VAK-694	QBX-258	Phase 2 Clinical	Novartis Pharma Ag	Asthma; Lymphedema	詳細
OCH-NCNP1	OCH-NCNP1	Phase 2 Clinical	Keio University	Crohn Disease; Multiple Sclerosis	詳細
Ompekimig	PF-07264660	Phase 2 Clinical	Pfizer Inc	Dermatitis, Atopic	詳細
AUP1602-C	AUP-16; AUP1602-C	Phase 2 Clinical	Aurealis	Diabetic Foot; Ulcer	詳細
Dupixent biosimilar (Chong Kun Dang Pharmaceutical)	CKD-706	Phase 1 Clinical	Chong Kun Dang Pharmaceutical Corp	Dermatitis, Atopic	詳細
Dupilumab biosimilar (China Resources Biopharma)		Phase 1 Clinical	China Resources Biopharmaceutical Co Ltd	Dermatitis, Atopic	詳細
Dupilumab biosimilar (Jiangsu Jingxing Pharma)		Phase 1 Clinical	Jiangsu Jingxing Pharmaceutical Technology Co Ltd	Dermatitis, Atopic	詳細
Dupilumab biosimilar (Chengdu Kanghong)	KH-816; KH816	Phase 1 Clinical	Chengdu Kanghong Biotechnologies Co Ltd	Dermatitis, Atopic	詳細
Dupilumab biosimilar (Jushi Biopharma)		Phase 1 Clinical	Jushi Biopharmaceutical Co Ltd	Dermatitis, Atopic	詳細
Dupilumab biosimilar (Bio-Thera Solutions)	BAT2406; BAT-2406	Phase 1 Clinical	Bio-Thera Solutions Ltd	Asthma; Dermatitis, Atopic; Eosinophilic Esophagitis; Nasal Polyps; Prurigo Nodularis; Sinusitis	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Dupilumab	REGN-668; SAR-231893	Approved	Regeneron Pharmaceuticals Inc, Sanofi	Dupixent, 达必妥	United States	Dermatitis, Atopic	Regeneron Pharmaceuticals Inc	2017-03-28	Allergic Fungal Rhinosinusitis; Alopecia Areata; Angioedema; Aspergillosis, Allergic Bronchopulmonary; Asthma; Asthma, Aspirin-Induced; Chronic Urticaria; Colitis, Ulcerative; Conjunctivitis, Allergic; Coronavirus Disease 2019 (COVID-19); Dermatitis; Dermatitis, Atopic; Eczema; Eosinophilic Esophagitis; Eosinophilic gastroenteritis (EG); Genetic Diseases, Inborn; Hypereosinophilic Syndrome; Hypersensitivity; Hypersensitivity, Immediate; Keloid; Keratoconjunctivitis; Lichenoid Eruptions; Milk Hypersensitivity; Nasal Polyps; Nephrotic Syndrome; Neurodermatitis; Paranasal Sinus Diseases; Peanut Hypersensitivity; Pemphigoid, Bullous; Prostatic Neoplasms; Prurigo; Prurigo Nodularis; Pruritus; Pulmonary Disease, Chronic Obstructive; Respiration Disorders; Respiratory Sounds; Respiratory Tract Diseases; Rhinitis, Allergic; Scleroderma, Localized; Sinusitis; Skin Diseases; Skin Diseases, Eczematous; Sleep Apnea Syndromes; Urticaria	詳細
Berdazimer sodium	NVN-1000-SB-206-Novan; SB-206; MAP3-NONOate - SB-206; NVN1000-SB206; SB-019; NI-MC101; SB-207; SB-208; SB-204; SB-414	Approved	University Of North Carolina At Chapel Hill	KINSOLUSTM, Zelsuvmi, ZELSUVMI	United States	Molluscum Contagiosum	Lnhc Inc	2024-01-05	Acne Vulgaris; Condylomata Acuminata; Dermatitis, Atopic; Molluscum Contagiosum; Psoriasis; Tinea Pedis	詳細

レビュー

M***e2023-06-15
3評価
IL-4 [Biotinylated] : IL-4Rα Inhibitor Screening ELISA Kit
We have used this kit to profile compounds. This kit is both reliable and easy to use, and it shipped quickly. The 96 test kit is also amenable to scaling to a 384 well format for additional screening capabilities. In our experience, the customer service at ACRO has always been prompt when inquiring about when items will be restocked and when they have shipped.