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IL-7 R alpha

IL-7 R alpha 詳細

英語名	Interleukin-7 receptor subunit alpha	市販薬剤の数	0
治験薬の数	8	ターゲットの別称	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
研究＆開発段階	Phase 2 Clinical

英語名	Interleukin-7 receptor subunit alpha
ターゲットの別称	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
市販薬剤の数	0
治験薬の数	8
研究＆開発段階	Phase 2 Clinical

IL-7 R alpha 製品リスト

属性
Protein (7)
製品ライブラリ
オンライン (7)
種
Human (5)Mouse (1)Cynomolgus (1)
タグ
Mouse IgG Fc Tag (2)Fc Tag (2)Fc Tag & Avi Tag (1)His Tag (2)
マーカー
Unconjugated (6)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
HOT IL7-H5258	Human	HEK293	Human IL-7 R alpha / CD127 Protein (I66T, V138I), Mouse IgG2a Fc Tag
HOT IL7-H52H7	Human	HEK293	Human IL-7 R alpha / CD127 Protein, His Tag, low endotoxin
HOT IL7-H82F9	Human	HEK293	Biotinylated Human IL-7 R alpha / CD127 Protein, Fc,Avitag™
HOT ILA-H525a	Human	HEK293	Human IL-7 R alpha / CD127 Protein, Fc Tag
IL7-H5255	Human	HEK293	Human IL-7 R alpha Protein, Mouse IgG2a Fc Tag
ILR-M5253	Mouse	HEK293	Mouse IL-7 R alpha / CD127 Protein, Fc Tag
IL7-C52H8	Cynomolgus	HEK293	Cynomolgus IL-7 R alpha / CD127 Protein, His Tag (MALS verified)

総数量7

IL-7 R alphaバックグランド

Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

IL-7 R alpha分子の別称

IL7Ra,CD127

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
CYT-107	CYT-107; CYT-99-007; rhIL-7	Phase 2 Clinical	Revimmune Inc	Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Catheter-Related Infections; Coronavirus Disease 2019 (COVID-19); Hepatitis B, Chronic; Hepatitis C; HIV Infections; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphopenia; Metastatic breast cancer; Multiple Myeloma; Mycobacterium Infections, Nontuberculous; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Kaposi; Sepsis; Shock, Septic; Skin Melanoma; T-Lymphocytopenia, Idiopathic CD4-Positive; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms	詳細
Lusvertikimab	OSE-127; S-95011; Effi-7; OSE-217	Phase 2 Clinical	Effimune	Colitis, Ulcerative; Sjogren's Syndrome	詳細
Efineptakin alfa	TJ-107; GX-I7; NT-I7	Phase 2 Clinical	Gannex Pharma Co Ltd	Astrocytoma; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Esophageal Neoplasms; Glioblastoma; Glioma; Gliosarcoma; HIV Infections; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Leukoencephalopathy, Progressive Multifocal; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphopenia; Melanoma; Multiple Myeloma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Plasmablastic Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	詳細
ASP-9801	ASP-9801	Phase 1 Clinical	Astellas Pharma Inc	Neoplasm Metastasis; Neoplasms; Solid tumours	詳細
PF-06342674	RN-168; PF-6342674; PF-06342674; ZB-168	Phase 1 Clinical	Pfizer Inc	Diabetes Mellitus, Type 1; Multiple Sclerosis	詳細
CD19-IL7Ra CAR-T cells therapy (Chulalongkorn University)	CMD-63; CMD63	Phase 1 Clinical	Chulalongkorn University	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	詳細
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University)		Phase 1 Clinical	Chulalongkorn University, King Chulalongkorn Memorial Hospital	Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Neoplasms; Solid tumours	詳細
MDK-703	MDK-703	Phase 1 Clinical	Medikine Inc	Solid tumours	詳細