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IL-7 R alpha & TSLP R

IL-7 R alpha & TSLP R 詳細

英語名	Interleukin-7 receptor subunit alpha	市販薬剤の数	0
治験薬の数	8	ターゲットの別称	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
研究＆開発段階	Phase 2 Clinical

英語名	Interleukin-7 receptor subunit alpha
ターゲットの別称	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
市販薬剤の数	0
治験薬の数	8
研究＆開発段階	Phase 2 Clinical

IL-7 R alpha & TSLP R 製品リスト

属性
Protein (3)Cell (1)Kits (1)
製品ライブラリ
オンライン (5)
種
Human (4)Mouse (1)
タグ
Fc Tag (3)- (2)
マーカー
Unconjugated (3)- (2)

製品番号	種	発現システム	製品説明
HOT CHEK-ATF045	Human	HEK293	Human TSLP R (Luc) HEK293 Reporter Cell
HOT EP-129	Human	-	TSLP [Biotinylated] : IL-7Rα & TSLP R Inhibitor Screening ELISA Kit
HOT ILR-H5255	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified)
ILR-H525x	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag
ILR-M5257	Mouse	HEK293	Mouse IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag

総数量5

IL-7 R alpha & TSLP Rバックグランド

TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.

IL-7 R alpha & TSLP R分子の別称

IL7Ra,CD127,TSLP R,CRLF2,IL-XR,ILXR,p2RY8,CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
CYT-107	CYT-107; CYT-99-007; rhIL-7	Phase 2 Clinical	Revimmune Inc	Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Catheter-Related Infections; Coronavirus Disease 2019 (COVID-19); Hepatitis B, Chronic; Hepatitis C; HIV Infections; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphopenia; Metastatic breast cancer; Multiple Myeloma; Mycobacterium Infections, Nontuberculous; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Kaposi; Sepsis; Shock, Septic; Skin Melanoma; T-Lymphocytopenia, Idiopathic CD4-Positive; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms	詳細
Lusvertikimab	OSE-127; S-95011; Effi-7; OSE-217	Phase 2 Clinical	Effimune	Colitis, Ulcerative; Sjogren's Syndrome	詳細
Efineptakin alfa	TJ-107; GX-I7; NT-I7	Phase 2 Clinical	Gannex Pharma Co Ltd	Astrocytoma; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Esophageal Neoplasms; Glioblastoma; Glioma; Gliosarcoma; HIV Infections; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Leukoencephalopathy, Progressive Multifocal; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphopenia; Melanoma; Multiple Myeloma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Plasmablastic Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	詳細
ASP-9801	ASP-9801	Phase 1 Clinical	Astellas Pharma Inc	Neoplasm Metastasis; Neoplasms; Solid tumours	詳細
PF-06342674	RN-168; PF-6342674; PF-06342674; ZB-168	Phase 1 Clinical	Pfizer Inc	Diabetes Mellitus, Type 1; Multiple Sclerosis	詳細
CD19-IL7Ra CAR-T cells therapy (Chulalongkorn University)	CMD-63; CMD63	Phase 1 Clinical	Chulalongkorn University	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	詳細
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University)		Phase 1 Clinical	Chulalongkorn University, King Chulalongkorn Memorial Hospital	Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Neoplasms; Solid tumours	詳細
MDK-703	MDK-703	Phase 1 Clinical	Medikine Inc	Solid tumours	詳細