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Latent TGF-beta 2

Latent TGF-beta 2 詳細

英語名	Transforming growth factor beta 2	市販薬剤の数	0
治験薬の数	6	ターゲットの別称	TGF-beta-2，BSC-1 Cell Growth Inhibitor，Polyergin，Glioblastoma-Derived T-Cell Suppressor Factor，Cetermin，LDS4，TGFB2，Transforming Growth Factor， Beta 2，Transforming Growth Factor Beta-2 Proprotein，TGF-Beta2，Transforming Growth Factor Beta 2，G-TSF，Transforming Growth Factor beta2，LAP，Prepro-Transforming Growth Factor Beta-2
研究＆開発段階	Phase 3 Clinical

英語名	Transforming growth factor beta 2
ターゲットの別称	TGF-beta-2，BSC-1 Cell Growth Inhibitor，Polyergin，Glioblastoma-Derived T-Cell Suppressor Factor，Cetermin，LDS4，TGFB2，Transforming Growth Factor， Beta 2，Transforming Growth Factor Beta-2 Proprotein，TGF-Beta2，Transforming Growth Factor Beta 2，G-TSF，Transforming Growth Factor beta2，LAP，Prepro-Transforming Growth Factor Beta-2
市販薬剤の数	0
治験薬の数	6
研究＆開発段階	Phase 3 Clinical

Latent TGF-beta 2 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
TG2-H5243	Human	HEK293	Human Latent TGF-beta 2 / TGFB2 Protein, His Tag

総数量1

Latent TGF-beta 2バックグランド

Transforming growth factor beta 2 ( TGFB2) is also known as TGF-β2, G-TSF, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB2 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB2 protein can inhibit the T cell growth by IL-2-dependent. and can inhibit immune surveillance during tumor development, the protein promoting tumor growth with an autocrine manner. TGF-β2 can affect the viability of killer cells and reduce the expression of IL-2, IL-6, IL-10, IFN-γ and other cytokines.TGFB2 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages.

Latent TGF-beta 2分子の別称

Latent TGFB2,MGC116892,TGFβ2,TGF-beta2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Trabedersen	AP 2/09-DS; AP-12009; OT-201; AP-2/09; AP-2/09-DS; OT-101	Phase 3 Clinical	Isarna Therapeutics Gmbh	Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Diffuse Intrinsic Pontine Glioma; Glioblastoma; Lung Neoplasms; Melanoma; Mesothelioma; Pancreatic Neoplasms; Solid tumours	詳細
Bintrafusp alfa	M-7824; GSK-4045154; MSB-0011359C	Phase 3 Clinical	Merck Serono	Anus Neoplasms; Biliary Tract Neoplasms; Brain metastases; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Esthesioneuroblastoma, Olfactory; Gallbladder Neoplasms; Ganglioglioma; Head and Neck Neoplasms; Hematologic Neoplasms; Intestinal Neoplasms; Lung Neoplasms; Lymphoma; Melanoma; Metastatic breast cancer; Microsatellite Instability; Nasopharyngeal Carcinoma; Neoplasm Metastasis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Nose Neoplasms; Oropharyngeal Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Penile Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Respiratory papillomatosis; Sarcoma; Sarcoma, Kaposi; Skin Melanoma; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Thymic epithelial tumor; Thymoma; Thymus Neoplasms; Triple Negative Breast Neop	詳細
Nisevokitug	NIS-793	Phase 3 Clinical	Xoma Corp	Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Kidney Neoplasms; Lung Neoplasms; Myelodysplastic Syndromes; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential	詳細
ISTH-0036	ISTH-0036	Phase 2 Clinical	Isarna Therapeutics Gmbh	Diabetic macular oedema; Glaucoma, Open-Angle; Wet Macular Degeneration	詳細
Tosposertib phosphate	TU-2218; NCE401; NCE-401	Phase 2 Clinical	TiumBio Co Ltd	Idiopathic Pulmonary Fibrosis; Solid tumours	詳細
LP-008	LP-008	Phase 1 Clinical	Lepu Biopharma Co Ltd	Solid tumours	詳細