言語を選択

LIF

LIF 詳細

英語名	Leukemia inhibitory factor	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	LIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
研究＆開発段階	Phase 2 Clinical

英語名	Leukemia inhibitory factor
ターゲットの別称	LIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 2 Clinical

LIF 製品リスト

属性
Protein (6)
製品ライブラリ
オンライン (6)
種
Human (4)Mouse (2)
タグ
Tag Free (3)His Tag (2)His Tag & Avi Tag (1)
マーカー
Unconjugated (5)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
HOT LIF-H521b	Human	HEK293	Human LIF Protein, Tag Free
HOT LIF-H52H3	Human	HEK293	Human LIF Protein, His Tag (MALS verified)
HOT LIF-H82E2	Human	HEK293	Biotinylated Human LIF Protein, His,Avitag™
LIF-H5215	Human	HEK293	Human LIF Protein, premium grade
LIF-M5219	Mouse	HEK293	Mouse LIF Protein, Tag Free (MALS verified)
LIF-M5227	Mouse	HEK293	Mouse LIF Protein, His Tag (MALS verified)

総数量6

LIFバックグランド

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF分子の別称

LIF,CDF,DIA,HILDA,MLPLI

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Falbikitug	AZD-0171; MSC-1	Phase 2 Clinical	Astrazeneca Plc	Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours	詳細
JAB-BX300	JAB-BX300	Phase 2 Clinical	Jacobio Pharmaceuticals Co Ltd	Pancreatic Neoplasms; Solid tumours	詳細