LIV-1

LIV-1 詳細

英語名Zinc transporter ZIP6市販薬剤の数0
治験薬の数2ターゲットの別称LIV-1,LIV1,LIV-1 Protein, Estrogen Regulated,Solute Carrier Family 39 (Metal Ion Transporter), Member 6,Zrt- and Irt-like protein 6,SLC39A6,Estrogen-regulated protein LIV-1,ZIP-6,Zinc transporter ZIP6,Solute Carrier Family 39 (Zinc Transporter), Member 6,Solute carrier family 39 member 6
研究&開発段階Phase 2 Clinical
英語名Zinc transporter ZIP6
ターゲットの別称LIV-1,LIV1,LIV-1 Protein, Estrogen Regulated,Solute Carrier Family 39 (Metal Ion Transporter), Member 6,Zrt- and Irt-like protein 6,SLC39A6,Estrogen-regulated protein LIV-1,ZIP-6,Zinc transporter ZIP6,Solute Carrier Family 39 (Zinc Transporter), Member 6,Solute carrier family 39 member 6
市販薬剤の数0
治験薬の数2
研究&開発段階Phase 2 Clinical

LIV-1 製品リスト

  • 属性

    Protein (14)

  • 製品ライブラリ

    オンライン (14)

  • Human (7)Cynomolgus (3)Rat (1)Mouse (2)Rhesus macaque (1)

  • タグ

    Fc Tag (4)His Tag (6)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)- (1)

  • マーカー

    Unconjugated (11)Biotin-labeled (3)

LIV-1バックグランド

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

LIV-1分子の別称

SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6

抗体購入プラットフォーム

プロジェクトステージタイプ由来疾患領域適応症
LIV-1 mAb - 01PCCMonoclonalHumanized MouseSolid TumorColorectal cancer,Breast cancer

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
Ladiratuzumab vedotinSGN-LIV1A; MK-6440; MK6440Phase 2 ClinicalMerck Sharp & Dohme Corp, Seagen IncBreast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Squamous Cell Carcinoma; Gastroesophageal Junction Neoplasms; Melanoma; Metastatic breast cancer; Prostatic Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms
詳細
LaventatugBRY-812Phase 2 ClinicalZhejiang BioRay Biopharmaceuticals Co LtdNeoplasms; Solid tumours
詳細

レビュー

  • J***g2022-04-13
    1評価
    When I was searching for this protein, there were not many options until I found ACRO. Very happy about various species as well as tag choices. ELISA results are reproducible and consistent. The delivery was fast whereas others may take longer. The product information is clear and comprehensive, which is very important for the research.
  • 詳細
  • 製品リスト
  • レビュー
  • 治験薬に関する情報
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