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LRP-1

LRP-1 詳細

英語名	Low density lipoprotein receptor-related protein-1	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	Apolipoprotein E Receptor，TbetaR-V/LRP-1/IGFBP-3 Receptor，Type V Tgf-Beta Receptor，CD91 Antigen，APOER，Alpha-2-Macroglobulin Receptor，IGFBP3R1，IGFBP3R，TGFBR5，IGFBP-3R，LRP1A，CD91，A2MR，Prolow-Density Lipoprotein Receptor-Related Protein 1，Low Density Lipoprotein Receptor-Related Protein 1
研究＆開発段階	Preclinical

英語名	Low density lipoprotein receptor-related protein-1
ターゲットの別称	Apolipoprotein E Receptor，TbetaR-V/LRP-1/IGFBP-3 Receptor，Type V Tgf-Beta Receptor，CD91 Antigen，APOER，Alpha-2-Macroglobulin Receptor，IGFBP3R1，IGFBP3R，TGFBR5，IGFBP-3R，LRP1A，CD91，A2MR，Prolow-Density Lipoprotein Receptor-Related Protein 1，Low Density Lipoprotein Receptor-Related Protein 1
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

LRP-1 製品リスト

属性
Protein (5)
製品ライブラリ
オンライン (5)
種
Human (5)
タグ
Fc Tag (3)His Tag & Avi Tag (2)
マーカー
Unconjugated (3)Biotin-labeled (2)

製品番号	種	発現システム	製品説明
HOT LR1-H5256	Human	HEK293	Human LRP-1 / cluster Ⅳ Protein, Fc Tag
LR1-H5254	Human	HEK293	Human LRP-1 / cluster Ⅱ Protein, Fc Tag, low endotoxin (MALS verified)
LR1-H5255	Human	HEK293	Human LRP-1 / cluster Ⅲ Protein, Fc Tag (MALS verified)
LR1-H82E3	Human	HEK293	Biotinylated Human LRP-1 / cluster Ⅲ Protein, His,Avitag™ (MALS & BLI verified)
LR1-H82E4	Human	HEK293	Biotinylated Human LRP-1 / cluster Ⅳ Protein, His,Avitag™ (BLI verified)

総数量5

LRP-1バックグランド

Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.