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M-CSF R

M-CSF R 詳細

英語名	Colony stimulating factor 1 receptor	市販薬剤の数	11
治験薬の数	36	ターゲットの別称	CSFR，CD115 Antigen，FMS Proto-Oncogene，EC 2.7.10.1，CSF1R，Proto-Oncogene C-Fms，Macrophage Colony-Stimulating Factor 1 Receptor，FIM2，McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog，CSF-1R，C-FMS，Macrophage Colony Stimulating Factor I Receptor，CD115，HDLS，EC:2.7.10.1，EC 2.7.10，CSF-1-R，CSF-1 Receptor，FMS，BANDDOS，M-CSF-R，Colony Stimulating Factor 1 Receptor
研究＆開発段階	Approved

英語名	Colony stimulating factor 1 receptor
ターゲットの別称	CSFR，CD115 Antigen，FMS Proto-Oncogene，EC 2.7.10.1，CSF1R，Proto-Oncogene C-Fms，Macrophage Colony-Stimulating Factor 1 Receptor，FIM2，McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog，CSF-1R，C-FMS，Macrophage Colony Stimulating Factor I Receptor，CD115，HDLS，EC:2.7.10.1，EC 2.7.10，CSF-1-R，CSF-1 Receptor，FMS，BANDDOS，M-CSF-R，Colony Stimulating Factor 1 Receptor
市販薬剤の数	11
治験薬の数	36
研究＆開発段階	Approved

M-CSF R 製品リスト

属性
Protein (13)
製品ライブラリ
オンライン (13)
種
Human (6)Mouse (3)Cynomolgus (2)Canine (1)Rabbit (1)
タグ
His Tag (7)Fc Tag (3)His Tag & Avi Tag (2)Mouse IgG Fc Tag (1)
マーカー
Unconjugated (9)Biotin-labeled (2)AF488 Labeled (1)AF647 Labeled (1)

製品番号	種	発現システム	製品説明
HOT CSR-H5228	Human	HEK293	Human M-CSF R / CSF1R / CD115 Protein, His Tag (MALS verified)
HOT CSR-H82E0	Human	HEK293	Biotinylated Human M-CSF R / CSF1R / CD115 Protein, Avitag™,His Tag
HOT CSR-C5252	Cynomolgus	HEK293	Cynomolgus M-CSF R / CSF1R / CD115 Protein, Fc Tag
HOT CSR-C52E1	Cynomolgus	HEK293	Cynomolgus M-CSF R / CSF1R / CD115 Protein, His Tag
CSR-H5255	Human	HEK293	Human M-CSF R / CSF1R / CD115 Protein, Mouse IgG2a Fc Tag (MALS verified)
CSR-H5258	Human	HEK293	Human M-CSF R / CSF1R / CD115 Protein, Fc Tag, low endotoxin
CSR-HA2H3	Human	HEK293	Alexa Fluor™ 488-Labeled Human M-CSF R / CSF1R / CD115 Protein, His TagStar Staining (HPLC verified)
CSR-HA2H4	Human	HEK293	Alexa Fluor™ 647-Labeled Human M-CSF R / CSF1R / CD115 Protein, His TagStar Staining
CSR-M5256	Mouse	HEK293	Mouse M-CSF R / CSF1R / CD115 Protein, Fc Tag, low endotoxin
CSR-M52E7	Mouse	HEK293	Mouse M-CSF R / CSF1R / CD115 Protein, His Tag

総数量13

M-CSF Rバックグランド

Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the typeⅢ subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation . Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

M-CSF R分子の別称

CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Simmitinib hydrochloride	SOMCL-15-290	Phase 3 Clinical	Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences	Breast Neoplasms; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gastroesophageal Junction Neoplasms; Neoplasms; Solid tumours; Stomach Neoplasms	詳細
Seralutinib	PK-10571; GB-002	Phase 3 Clinical	Gilead Sciences Inc	Pulmonary Arterial Hypertension	詳細
Chiauranib	CS-2164; CS2164	Phase 3 Clinical	Shenzhen Chipscreen Biosciences Co Ltd	Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Lymphoma, Non-Hodgkin; Neoplasms; Ovarian Neoplasms; Sarcoma; Small Cell Lung Carcinoma; Solid tumours; Triple Negative Breast Neoplasms	詳細
Emactuzumab	RO-5509554; RG-7155; 6FY6EI1X8R	Phase 3 Clinical	F. Hoffmann-La Roche Ltd	Carcinoma; Carcinoma, Squamous Cell; Giant Cell Tumor of Tendon Sheath; Head and Neck Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Prostatic Neoplasms; Solid tumours	詳細
BS-001	BS-001; BS001; oHSV-2; OH-2; OH2; OH2 injection; oHSV2hGM-CSF	Phase 3 Clinical	Wuhan Binhui Biotechnology Co Ltd	Bile Duct Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Digestive System Neoplasms; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Liver Diseases; Liver Neoplasms; Lung Neoplasms; Lymphoma; Melanoma; Neoplasms; Pancreatic Neoplasms; Sarcoma; Solid tumours; Urinary Bladder Neoplasms	詳細
Simmitinib	SYHA-1817	Phase 3 Clinical	CSPC Pharmaceutical Group Ltd	Biliary Tract Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Stomach Neoplasms	詳細
OPN-7486	PLX-7486; PLX7486-TsOH	Phase 2 Clinical	Plexxikon Inc	Giant Cell Tumor of Tendon Sheath; Neoplasms; Solid tumours	詳細
Cabiralizumab	FPA-008; ONO-4687; BMS-986227	Phase 2 Clinical	Five Prime Therapeutics Inc	Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Giant Cell Tumor of Tendon Sheath; Glioma; Head and Neck Neoplasms; Lymphoma, T-Cell, Peripheral; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms	詳細
Narazaciclib	HX-301; ON-123300	Phase 2 Clinical	Temple University	Breast Neoplasms; Endometrial Neoplasms; Glioblastoma; Glioma; Multiple Myeloma; Solid tumours	詳細
Derazantinib	ARQ-087.2HCl; AQ-14741087; ARQ-087; BAL-087	Phase 2 Clinical	Arqule Inc	Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Transitional Cell; Cholangiocarcinoma; Solid tumours; Stomach Neoplasms; Urogenital Neoplasms	詳細
C-019199	C019199	Phase 2 Clinical	Fujian Haixi Pharmaceuticals Co Ltd	Breast Neoplasms; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Giant Cell Tumor of Tendon Sheath; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms	詳細
Elzovantinib	TPX-0022	Phase 2 Clinical	Turning Point Therapeutics Inc	Carcinoma, Non-Small-Cell Lung; Solid tumours; Stomach Neoplasms	詳細
AMB-066	AMB-066	Phase 2 Clinical	AmMax Bio Inc	Colorectal Neoplasms	詳細
Inhaled Nintedanib – dry powder (Avalyn Pharma)	AP02; AP 02 DP; AP-02; AP02-DP	Phase 2 Clinical	Avalyn Pharma Inc	Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Respiratory Tract Diseases	詳細
BS-008	BS001/BS006; BS001+BS006	Phase 2 Clinical	Wuhan Binhui Biotechnology Co Ltd	Colorectal Neoplasms; Sarcoma; Solid tumours	詳細
Enrupatinib	FB-1071; 4B71-01; EI-1071	Phase 2 Clinical	Elixiron Immunotherapeutics Inc	Alzheimer Disease; Amyotrophic Lateral Sclerosis; Giant Cell Tumor of Tendon Sheath; Nervous System Diseases	詳細
[11C]CPPC		Phase 2 Clinical	Johns Hopkins University	Amyotrophic Lateral Sclerosis; Post-Acute COVID-19 Syndrome	詳細
AMB-051	AMB 053; AMB-055; AMG-820; AMB-051; AMB-05X	Phase 2 Clinical	Amgen Inc	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Giant Cell Tumor of Tendon Sheath; Idiopathic Pulmonary Fibrosis; Neoplasms; Pancreatic Neoplasms; Solid tumours; Synovitis, Pigmented Villonodular; Testicular Neoplasms	詳細
BC-006	BC-006; BC006; ADG125; ADG-125	Phase 2 Clinical	Adagene Inc	Giant Cell Tumor of Tendon Sheath; Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis; Solid tumours	詳細
Adrixetinib	Q-702	Phase 2 Clinical	Lead Discovery Center GmbH, Max Planck Institute of Biochemistry, Vichem Chemie	Blastic Plasmacytoid Dendritic Cell Neoplasm; Carcinoma, Hepatocellular; Central Nervous System Lymphoma; Erdheim-Chester Disease; Esophageal Neoplasms; Graft vs Host Disease; Hematologic Neoplasms; Histiocytic Sarcoma; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Follicular; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Myelodysplastic Syndromes; Neoplasm Metastasis; Neoplasms; Neoplasms, Plasma Cell; Solid tumours; Stomach Neoplasms; Uterine Cervical Neoplasms; Waldenstrom Macroglobulinemia	詳細
SYHA-1813	SYHA1813	Phase 2 Clinical	Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Runshi Pharmaceutical Technology Co Ltd	Brain metastases; Carcinoma, Renal Cell; Colorectal Neoplasms; Giant Cell Tumor of Tendon Sheath; Glioma; Gliosarcoma; Liver Neoplasms; Lung Neoplasms; Meningioma; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms; Thyroid Neoplasms	詳細
LY-3022855	IMC-CS4; LY-3022855	Phase 1 Clinical	Eli Lilly And Company	Melanoma; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours	詳細
PMI-04	PMI-04	Phase 1 Clinical	Precision Molecular Inc	Nerve Degeneration; Neuroinflammatory Diseases	詳細
HH185	3D-185; 3-D185; HH-185; 3D185	Phase 1 Clinical	ShangHai HaiHe Biopharma Co Ltd, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Medicilon Inc	Solid tumours	詳細
Edicotinib	PRV-6527; JNJ-244; JNJ-40346527-AAC-G-002; JNJ-40346527; JNJ-527	Phase 1 Clinical	Johnson & Johnson	Alzheimer Disease; Arthritis, Rheumatoid; Cognitive Dysfunction; Crohn Disease; Hodgkin Disease; Leukemia, Myeloid, Acute; Prostatic Neoplasms	詳細
Pamufetinib	TAS-115	Phase 1 Clinical	Otsuka Pharmaceutical Co Ltd, Taiho Pharmaceutical Co Ltd	Neoplasms	詳細
JDB-383	JDB-383	Phase 1 Clinical	Shanghai Jiabao Yaoyin Pharmaceutical Technology Co Ltd	Giant Cell Tumor of Tendon Sheath	詳細
HMPL-653	HMPL-653	Phase 1 Clinical		Giant Cell Tumor of Tendon Sheath; Solid tumours; Testicular Neoplasms	詳細
AK-150 (Akeso)	AK150; AK-150	Phase 1 Clinical		Solid tumours	詳細
Nintedanib Esylate Inhalation Powder(Cspc)		Phase 1 Clinical	Cspc-Nbp Pharmaceutical Co Ltd	Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis	詳細
MNKD-201	MNKD-201; MKND-201	Phase 1 Clinical	MannKind Corp	Idiopathic Pulmonary Fibrosis	詳細
ETH-155036	ETH-155036; ETH155036	Phase 1 Clinical	Shengke Pharmaceutical (Jiangsu) Co Ltd	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	詳細
ND-003 (NewDEL Biotech)	ND003 (NewDEL Biotech); ND-003 (NewDEL Biotech); ND003; JND-5932	Phase 1 Clinical	Jinan University, Shenzhen NewDEL Biotech Co Ltd	Dermatitis, Atopic; Gastrointestinal Stromal Tumors; Idiopathic Pulmonary Fibrosis; Neoplasms; Pulmonary Fibrosis; Renal fibrosis; Renal Insufficiency, Chronic; Solid tumours	詳細
Caflanone	FBL-03G	Phase 1 Clinical	Flavocure Biotech Inc	Pancreatic Neoplasms	詳細
TT-00420/Atezolizumab		Phase 1 Clinical	TransThera Sciences (Nanjing) Inc	Gastrointestinal Neoplasms	詳細
AGX-0073	AGX-0073	Phase 1 Clinical	Shanghai Aojian Biological Technology Co Ltd	Solid tumours	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Vimseltinib	DCC-3014; DP-6865	Approved	Deciphera Pharmaceuticals Llc	ROMVIMZA	United States	Giant Cell Tumor of Tendon Sheath	Deciphera Pharmaceuticals Inc, Deciphera Pharmaceuticals	2025-02-14	Giant Cell Tumor of Tendon Sheath; Graft vs Host Disease; Neoplasms; Synovitis, Pigmented Villonodular	詳細
Regorafenib	DAST; BAY-73-4506	Approved	Bayer AG	Stivarga, Resihance	United States	Colorectal Neoplasms	Bayer Healthcare Pharmaceuticals Inc	2012-09-27	Adenocarcinoma; Adenoma; Bile Duct Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Esophageal adenocarcinoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gastrinoma; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Glucagonoma; Hemangiosarcoma; Insulinoma; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Melanoma; Meningioma; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma; Sarcoma, Ewing; Solid tumours; Somatostatinoma; Stomach Neoplasms; Thymoma; Thyroid Neoplasms	詳細
Nintedanib Esylate	BIBF-1120	Approved	C.H. Boehringer Sohn Ag & Co. Kg	Ofev, Vargatef	United States	Idiopathic Pulmonary Fibrosis	Boehringer Ingelheim International Gmbh	2014-10-15	Adenocarcinoma, Clear Cell; Appendiceal Neoplasms; Asbestosis; Astrocytoma; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colonic Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Endometrial Stromal Tumors; Esophageal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Glioblastoma; Gliosarcoma; Hepatic Insufficiency; Idiopathic Pulmonary Fibrosis; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Mesothelioma; Multiple Myeloma; Neoplasms; Oligodendroglioma; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Pulmonary Fibrosis; Radiation Pneumonitis; Rejection of lung transplantation; Sarcoma; Scleroderma, Systemic; Silicosis; Small Cell Lung Carcinoma; Solid tumours; systemic sclerosis-associated interstitial lung disease; Telangiectasia, Hereditary Hemorrhagic; Uterine Neoplasms	詳細
Pacritinib Citrate	ONX-0803; SB-1518	Approved	S*BIO Pte Ltd	VONJO, Epjevy, ENPAXIQ	United States	Primary Myelofibrosis	Sobi	2022-02-28	Bone Marrow Diseases; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Coronavirus Infections; Graft vs Host Disease; Hematologic Diseases; Hepatic Insufficiency; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Lymphoma; Lymphoma, B-Cell; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Myelodysplastic Syndromes; Myeloproliferative Disorders; Polycythemia Vera; Primary Myelofibrosis; Sarcoma, Kaposi; Thrombocythemia, Essential; Thrombocytopenia; VEXAS Syndome; Waldenstrom Macroglobulinemia	詳細
Pimicotinib	ABSK-021	Approved	ABbisko Therapeutics Co Ltd	贝捷迈	Mainland China	Giant Cell Tumor of Tendon Sheath	Merck Serono (Beijing) Pharmaceutical Co Ltd	2025-12-16	Amyotrophic Lateral Sclerosis; Giant Cell Tumor of Tendon Sheath; Graft vs Host Disease; Lung Neoplasms; Neoplasms; Pancreatic Neoplasms; Sarcoma; Solid tumours; Synovitis, Pigmented Villonodular; Triple Negative Breast Neoplasms	詳細
Surufatinib	HMPL-012	Approved		苏泰达, SULANDA	Mainland China	Neuroendocrine Tumors	Hutchison Medipharma Ltd	2020-12-29	Appendiceal Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Neuroendocrine; Hematologic Neoplasms; Hepatic Insufficiency; Intestinal Neoplasms; Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Renal Insufficiency; Sarcoma; Small Cell Lung Carcinoma; Solid tumours; Thyroid Neoplasms	詳細
Sunitinib Malate	PNU-290940AD; PHA-290940AD; SCAI-003; SU-010398; SU-11248; GB-102; PHA-290940; PNU-290940; SU-011248-L-malate salt	Approved	Pfizer Inc	Sutent, 索坦	United States	Gastrointestinal Stromal Tumors; Carcinoma, Renal Cell	Cppi Cv	2006-01-26	Abdominal Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Islet Cell; Adrenocortical Carcinoma; AIDS-Related Complex; Amyloidosis; Angioimmunoblastic T-cell Lymphoma; Astrocytoma; Barrett Esophagus; Brain metastases; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Acinar Cell; Carcinoma, Adenoid Cystic; Carcinoma, Adenosquamous; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Papillary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Choriocarcinoma; Chronic eosinophilic leukemia (CEL); Cognition Disorders; Colorectal Neoplasms; Diabetic macular oedema; Endodermal Sinus Tumor; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Fibrosarcoma; Gastrointestinal Stromal Tumors; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangi	詳細
Axatilimab	SNDX-6352; UCB-6352; INCA-34176; INCA034176; INCA-034176	Approved	Ucb	NIKTIMVO	United States	Graft vs Host Disease	Incyte Corp	2024-08-14	Bone Marrow Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Coronavirus Infections; Cytokine Release Syndrome; Graft vs Host Disease; Hodgkin Disease; Idiopathic Pulmonary Fibrosis; Leukemia, Myelogenous, Chronic; Leukemia, Myelomonocytic, Chronic; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms; Respiratory Distress Syndrome, Adult; Solid tumours; Triple Negative Breast Neoplasms	詳細
Pexidartinib	PLX-3397	Approved	Daiichi Sankyo Co Ltd	Turalio	United States	Giant Cell Tumor of Tendon Sheath	Daiichi Sankyo Inc	2019-08-02	Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Giant Cell Tumor of Tendon Sheath; Giant Cell Tumors; Glioblastoma; Hodgkin Disease; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Metastatic breast cancer; Neoplasm Metastasis; Neoplasms; Neurofibroma, Plexiform; Neurofibrosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Synovitis, Pigmented Villonodular	詳細
Mirimostim	P-100; CSF-HU	Approved	Jcr Pharmaceuticals Co Ltd	Costilate, Leukoprol	Japan	Neutropenia	Jcr Pharmaceuticals Co Ltd	1991-01-01	Neutropenia	詳細
Pazopanib Hydrochloride	GSK-786034; GW-786034B; SB-786034; GW-786034	Approved	Glaxosmithkline Plc, Novartis Pharma Ag	维全特, Armala, Votrient, Patorma	United States	Carcinoma, Renal Cell; Sarcoma	Novartis Pharma Ag	2009-10-19	Adenocarcinoma, Follicular; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Chondrosarcoma; Chondrosarcoma, Extraskeletal Myxoid; Choriocarcinoma; Colorectal Neoplasms; Dermatofibrosarcoma; Endodermal Sinus Tumor; Epistaxis; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Gastrinoma; Gastroenteropancreatic neuroendocrine tumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Glucagonoma; Hemangiosarcoma; Herpes Genitalis; Herpes Simplex; HIV Infections; Hormone-Resistant Prostate Neoplasms; Insulinoma; Leiomyosarcoma; Leukemia, Myeloid, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Macular Degeneration; Medullary thyroid cancer (MTC); Melanoma; Mesothelioma; Multiple Endocrine Neoplasia T	詳細