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MICB

MICB Overview

English NameMHC class I polypeptide-related sequence BApproved Drugs0
Drugs in Clinical Trials4Target Synonym
Highest Development StagePhase 1 Clinical
English NameMHC class I polypeptide-related sequence B
Target Synonym
Approved Drugs0
Drugs in Clinical Trials4
Highest Development StagePhase 1 Clinical

MICB Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
MIB-H52H3
Human
HEK293
Human MICB Protein, His Tag (MALS verified)
Total: 1
  • 1

MICB Background

Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
IsuventatugCLN-619Phase 1 ClinicalCullinan MICA CorpCarcinoma, Non-Small-Cell Lung; Multiple Myeloma; Solid tumours
Details
FT-536FT-536Phase 1 ClinicalFate Therapeutics IncAbdominal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Ovarian Neoplasms; Solid tumours
Details
FT-836FT-836; FT836Phase 1 ClinicalFate Therapeutics IncBreast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Endometrial Neoplasms; Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck
Details
DM-919DM-919; DM919Phase 1 ClinicalD2M Biotherapeutics IncNeoplasms; Solid tumours
Details
  • Product List
  • Clinical Drug Information
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