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MIS RII

MIS RII 詳細

英語名	Anti-Mullerian hormone receptor II	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
研究＆開発段階	Preclinical

英語名	Anti-Mullerian hormone receptor II
ターゲットの別称	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

MIS RII 製品リスト

属性
Protein (7)
製品ライブラリ
オンライン (7)
種
Human (5)Cynomolgus (1)Mouse (1)
タグ
Fc Tag (1)His Tag (3)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)
マーカー
Unconjugated (6)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
HOT MII-H5253	Human	HEK293	Human MIS RII Protein, Mouse IgG2a Fc Tag
HOT MII-H5258	Human	HEK293	Human MIS RII Protein, Fc Tag
HOT MII-H52H6	Human	HEK293	Human MIS RII Protein, His Tag
HOT MII-M52H6	Mouse	HEK293	Mouse MIS RII Protein, His Tag
MII-H5254	Human	HEK293	Human MIS RII Protein, Llama IgG2b Fc Tag, low endotoxin
MII-H82E3	Human	HEK293	Biotinylated Human MIS RII Protein, His,Avitag™
MII-C52H5	Cynomolgus	HEK293	Cynomolgus MIS RII Protein, His Tag

総数量7

MIS RIIバックグランド

MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

MIS RII分子の別称

MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor

レビュー

K***n2025-04-29
0評価
Human MIS RII Protein, Fc Tag
We purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.