Monoamine oxidase B Overview
Molecule Name
Monoamine oxidase B
Synonyms
MAOB, MAO-B,Monoamine Oxidase B,Monoamine oxidase type B
Drug Development Progress
Drugs in Clinical Trials13
Approved Drugs3
Highest Development StageApproved
Target Synonym
EC:1.4.3.4，EC 1.4.3，MAOB，Amine oxidase [flavin-containing] B，Monoamine Oxidase B，Monoamine Oxidase Type B，MAO-B，Adrenalin Oxidase，Tyramine Oxidase，MAO， Platelet，MAO， Brain，EC 1.4.3.4
Background
Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD).
Monoamine oxidase B Product List
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Project Cooperation
| Project Name | Drug Type | Therapeutic Area | Indication | Stage | Rights Area |
|---|---|---|---|---|---|
| Reversible MAOB Inhibitor | Small molecule | Neurological disease | Parkinson's disease | Phase I | Global |
- Project Name
- Reversible MAOB Inhibitor
- Drug Type
- Small molecule
- Therapeutic Area
- Neurological disease
- Indication
- Parkinson's disease
- Stage
- Phase I
- Rights Area
- Global