Nectin-2

Nectin-2 製品リスト

  • 属性

    Protein (6)

  • 製品ライブラリ

    オンライン (6)

  • Human (6)

  • タグ

    His Tag (1)Fc Tag (1)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Mouse IgG Fc Tag & Avi Tag (1)His Tag & Avi Tag (1)

  • マーカー

    Unconjugated (3)Biotin-labeled (3)

Nectin-2バックグランド

Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
COM-701COM-701Phase 2 ClinicalCompugen LtdSolid tumours; Head and Neck Neoplasms; Ovarian Neoplasms; Triple Negative Breast Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Lung Neoplasms
詳細
PM-1009PM1009Phase 2 ClinicalLiver Neoplasms; Solid tumours; Neoplasms; Lung Neoplasms; Carcinoma, Hepatocellular
詳細
SIM-0348SIM-0348Phase 1 ClinicalSimcere Pharmaceutical Group LtdSolid tumours; Neoplasms
詳細
GSK-4381562SRF-813; GSK-4381562; GSK-4381562A; GSK4381562A; GSK’562Phase 1 ClinicalSurface Oncology IncSolid tumours; Neoplasms
詳細
NM1FNM1F; TGI-2Phase 1 ClinicalHefei TG ImmunoPharma Co LtdOvarian Neoplasms; Solid tumours; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Melanoma
詳細
SHR-2002SHR-2002Phase 1 ClinicalSuzhou Suncadia Biopharmaceuticals Co Ltd, Shanghai Hengrui Pharmaceutical Co LtdNeoplasms
詳細
JS-009JS009; TAB009; JS-009Phase 1 ClinicalShanghai Junshi Biosciences Co LtdSolid tumours; Neoplasms
詳細
  • 製品リスト
  • 治験薬に関する情報
お問い合わせ

お問い合わせ
グローバル:+1 800-810-0816(Toll Free)

メールアドレス
order.jp@acrobiosystems.com

アクロバイオシステムズ株式会社
〒101-0051
東京都千代田区神田神保町1-32-8