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Neurogranin

Neurogranin 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
NEN-H5144	Human	E. coli	Human Neurogranin Protein, His Tag

総数量1

Neurograninバックグランド

Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Semzuvolimab	dB4; UB-421; mAb-B4	Phase 3 Clinical	United Biomedical Inc	HIV Infections	詳細
ITV 1(Nonindustrial source)	ITV-1	Phase 3 Clinical	Synexa Life Sciences, Immunotech Laboratories	HIV Infections	詳細
RB-0003	RB-0003; BNT-111	Phase 2 Clinical	Biontech Se, Tron	Melanoma	詳細
VRC-01-LS	VRC-HIVMAB-080-00-AB; VRC-01-LS	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	詳細
VRC-07-523	VRC-07-523-L S; VRC-HIVMAB075-00-AB; VRC-HIVMAB-075 -00-AB; VRC-07-523; TMB-380	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid), Taimed Biologics Inc	Acquired Immunodeficiency Syndrome; HIV Infections; Retroviridae Infections; Sexually Transmitted Diseases, Viral; HIV Seropositivity	詳細
GEN-009	GEN-009	Phase 2 Clinical	Genocea Biosciences Inc	Skin Melanoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Carcinoma, Non-Small-Cell Lung	詳細
Tregalizumab	hB-F5; BT-061	Phase 2 Clinical	Biotest Pharma Gmbh	Drug Hypersensitivity; Arthritis, Rheumatoid; Psoriasis; Asthma	詳細
MVA-EL	MVA-EBNA1/LMP2	Phase 2 Clinical	Chinese University Of Hong Kong (Cuhk), Cancer Research UK	Head and Neck Neoplasms; Stomach Neoplasms; Nasopharyngeal Neoplasms; Lymphoproliferative Disorders; Epstein-Barr Virus Infections; Lymphoma	詳細
VRC-HIVMAB091-00-AB	N6LS; Z258‐N6LS; VRC-HIVMAB091-00-AB	Phase 2 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	詳細
IMCY-0141	IMCY-0141	Phase 2 Clinical	Imcyse Sa	Multiple Sclerosis, Relapsing-Remitting	詳細
Autologous Regulatory Т-cell Therapy		Phase 2 Clinical	Institute Of Biophysics And Cell Engineering Of National Academy Of Sciences Of Belarus	Scleroderma, Systemic	詳細
CD4-directed chimeric antigen receptor engineered T-cells (Icell Gene)	CD4CAR (Icell Gene)	Phase 1 Clinical	Stony Brook University School Of Medicine, Icell Gene Therapeutics (Int'L) Ltd, University Of Louisville	Leukemia, Myelomonocytic, Chronic; Lymphoma, T-Cell; Leukemia, T-Cell	詳細
T-allo-10	T-allo-10	Phase 1 Clinical	Stanford University	Hematologic Diseases; Leukemia; Graft vs Host Disease; Hodgkin Disease; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin	詳細
Anti-CD4 CAR T-cell therapy (University of Pennsylvania)	CAR-C34ZFN	Phase 1 Clinical	University Of Pennsylvania	HIV Infections; HIV Seropositivity	詳細
10E8.4/iMab (Aaron Diamond AIDS Research Center)	TMB-370	Phase 1 Clinical	Aaron Diamond Aids Research Center For The City Of New York, Inc	HIV Infections	詳細
CALRLong36 peptide (Herlev Hospital)		Phase 1 Clinical	Herlev Hospital	Myeloproliferative Disorders	詳細
VRC-HIVMAB060-00-AB	VRC-HIVMAB060-00-AB; VRC01	Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections	詳細
VRC-HIVMAB0115-00-AB		Phase 1 Clinical	National Institute Of Allergy And Infectious Diseases (Niaid)	HIV Infections; HIV Seropositivity	詳細
SCRI-E2CAR_EGFRtv1	SCRI-E2CAR_EGFRtv1	Phase 1 Clinical	Umoja BioPharma Inc	Osteosarcoma	詳細
CD4^LVFOXP3 Treg-like cell therapy	CD4^LVFOXP3	Phase 1 Clinical	Stanford University	Polyendocrinopathies, Autoimmune	詳細
TMB-365	TMB-365	Phase 1 Clinical	Taimed Biologics Inc	HIV Infections	詳細
LB-1901	LB1901; LB-1901	Phase 1 Clinical		Lymphoma, T-Cell, Peripheral; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous	詳細
IT-1208 (Kyowa Hakko Kirin)	IT-1208	Phase 1 Clinical	Kyowa Hakko Kirin Co Ltd	Neoplasms	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Ibalizumab	Hu5A8; TMB-355; TNX-355; 5AB	Approved	Biogen Inc	特罗格佐, Trogarzo	United States	HIV Infections	Theratechnologies Inc	2018-03-06	HIV Infections	詳細