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Neuropilin-2

Neuropilin-2 詳細

英語名	Neuropilin 2	市販薬剤の数	0
治験薬の数	1	ターゲットの別称	Neuropilin-2，Vascular endothelial cell growth factor 165 receptor 2，NPN2，NP2，Neuropilin-2a(22)，Neuropilin-2b(0)，VEGF165R2，PRO2714，Neuropilin-2a(17)，Receptor For VEGF165 And Semaphorins Class3
研究＆開発段階	Phase 3 Clinical

英語名	Neuropilin 2
ターゲットの別称	Neuropilin-2，Vascular endothelial cell growth factor 165 receptor 2，NPN2，NP2，Neuropilin-2a(22)，Neuropilin-2b(0)，VEGF165R2，PRO2714，Neuropilin-2a(17)，Receptor For VEGF165 And Semaphorins Class3
市販薬剤の数	0
治験薬の数	1
研究＆開発段階	Phase 3 Clinical

Neuropilin-2 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
His Tag (1)His Tag & Avi Tag (1)
マーカー
Unconjugated (1)Biotin-labeled (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
NR2-H52H3	Human	HEK293	Human Neuropilin-2 / NRP2 Protein, His Tag (MALS verified)
NR2-H82E3	Human	HEK293	Biotinylated Human Neuropilin-2 / NRP2 Protein, His,Avitag™ (MALS verified)

総数量2

Neuropilin-2バックグランド

Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells.

Neuropilin-2分子の別称

Neuropilin-2,NRP2,VEGF165R2,Neuropilin2,Vascular endothelial cell growth factor 165 receptor 2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Efzofitimod	ATYR-1923; KRP-R120	Phase 3 Clinical	Atyr Pharma	Coronavirus Disease 2019 (COVID-19); Lung Diseases, Interstitial; Sarcoidosis, Pulmonary	詳細