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NGFR

NGFR 詳細

英語名	Low affinity neurotrophin receptor p75NTR	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
研究＆開発段階	Phase 2 Clinical

英語名	Low affinity neurotrophin receptor p75NTR
ターゲットの別称	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 2 Clinical

NGFR 製品リスト

属性
Protein (1)Cell (1)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
Fc Tag (1)- (1)
マーカー
Unconjugated (1)- (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
CHEK-ATP157	Human	HEK293	HEK293/Human NGFR Stable Cell Line
NGR-H5254	Human	HEK293	Human NGFR / TNFRSF16 Protein, Fc Tag (MALS & BLI verified)

総数量2

NGFRバックグランド

The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins(NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.

NGFR分子の別称

tumor necrosis factor receptor superfamily member 16; CD271; Gp80-LNGFR; member 16 nerve growth factor receptor; p75 ICD; p75 NTR

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
LM11A-31	LM11A-31; LM11A-31-BHS	Phase 2 Clinical	Pharmatrophix Inc	Alzheimer Disease; Supranuclear Palsy, Progressive	詳細
Recombinant human nerve growth factor (Xintrum Pharmacouticals)	rh-NGF; ZX1305; ZX-1305; ZX1305E; ZX-1305-E	Phase 2 Clinical	Jiangsu Zhongxin Pharmaceutical Co Ltd	Glaucoma, Open-Angle; Keratitis; Optic Nerve Injuries	詳細
Recombinant Human Nerve Growth Factor (Kerun Biopharmaceutical)		Phase 1 Clinical	Chongqing Kerun Biologic Pharmaceutical Development Co Ltd	Keratitis; Xerophthalmia	詳細