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NKp30

NKp30 製品リスト

属性
Protein (3)
製品ライブラリ
オンライン (3)
種
Human (3)
タグ
His Tag (1)Fc Tag (1)Llama IgG Fc Tag (1)
マーカー
Unconjugated (3)

製品番号	種	発現システム	製品説明
NC3-H5228	Human	HEK293	Human NKp30 / NCR3 / CD337 Protein, His Tag
NC3-H5256	Human	HEK293	Human NKp30 / NCR3 / CD337 Protein, Llama IgG2b Fc Tag, low endotoxin
NC3-H5259	Human	HEK293	Human NKp30 / NCR3 / CD337 Protein, Fc Tag

総数量3

NKp30バックグランド

Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.