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NRG1 Beta 1

NRG1 Beta 1 詳細

英語名	Neuregulin-1	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
研究＆開発段階	Preclinical

英語名	Neuregulin-1
ターゲットの別称	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

NRG1 Beta 1 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
Fc Tag (1)His Tag (1)
マーカー
Unconjugated (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
NR1-H5246	Human	HEK293	Human NRG1 Beta 1 Protein, His Tag, premium grade
NR1-H5268	Human	HEK293	Human NRG1 Beta 1 Protein, Fc Tag, premium grade

総数量2

NRG1 Beta 1バックグランド

NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.