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P-Selectin

P-Selectin 詳細

英語名	P-selectin	市販薬剤の数	1
治験薬の数	1	ターゲットの別称	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
研究＆開発段階	Approved

英語名	P-selectin
ターゲットの別称	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
市販薬剤の数	1
治験薬の数	1
研究＆開発段階	Approved

P-Selectin 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
His Tag (1)Fc Tag (1)
マーカー
Unconjugated (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
SEP-H5255	Human	HEK293	Human P-Selectin / CD62P Protein, Fc Tag
SEP-H52E4	Human	HEK293	Human P-Selectin / CD62P Protein, His Tag

総数量2

P-Selectinバックグランド

P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in α-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.

P-Selectin分子の別称

P-Selectin,CD62P,SELP,GMP-140

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Inclacumab	DSM-ACC-2641; RO 4905417; LC1004-002; DSM ACC2641; RG-1512; LC-1004-002; R-1512; PF-07940370; RO-4905417	Phase 3 Clinical	F. Hoffmann-La Roche Ltd, Genmab A/S	Anemia, Sickle Cell; Graft Occlusion, Vascular; Myocardial Infarction; Pain; Peripheral Arterial Disease	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Crizanlizumab	Sel-G-1; SEG-101; SEG101; Sel-G1	Approved	Selexys Pharmaceuticals Corp	Adakveo, Ryverna	United States	Anemia, Sickle Cell	Novartis Pharmaceuticals Corp	2019-11-15	Anemia, Sickle Cell; Coronavirus Disease 2019 (COVID-19); Leukoencephalopathies; Priapism; Primary Myelofibrosis	詳細

レビュー

V***u2023-07-13
2評価
Human P-Selectin / CD62P Protein, His Tag
AcroBio is our go to vendor, for our growing biotechnology start up. The customer service at acro bio is excellent, products have never failed in our labs. The specific product we got is the Human P-selectin/CD62P Protein His Tag which our lab has gotten multiple times and has not failed us. Thank you AcroBio for your amazing services, we appreciate you!