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PAR1

PAR1 Overview

English Name	Protease-activated receptor-1	Approved Drugs	0
Drugs in Clinical Trials	3	Target Synonym	Coagulation Factor II (Thrombin) Receptor，Proteinase-Activated Receptor 1，Coagulation Factor II Receptor，Protease-Activated Receptor 1，Protease Activated Receptor 1，Thrombin Receptor，HTR，Receptor， PAR-1，PAR1，F2R，Coagulation Factor II Thrombin Receptor，PAR-1，CF2R，TR
Highest Development Stage	Phase 1 Clinical

English Name	Protease-activated receptor-1
Target Synonym	Coagulation Factor II (Thrombin) Receptor，Proteinase-Activated Receptor 1，Coagulation Factor II Receptor，Protease-Activated Receptor 1，Protease Activated Receptor 1，Thrombin Receptor，HTR，Receptor， PAR-1，PAR1，F2R，Coagulation Factor II Thrombin Receptor，PAR-1，CF2R，TR
Approved Drugs	0
Drugs in Clinical Trials	3
Highest Development Stage	Phase 1 Clinical

PAR1 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (3)
Tag
- (1)GFP Tag (1)His Tag & Flag Tag (1)
Conjugate
Unconjugated (2)GFP Fusion (1)

Cat. No.	Species	Host	Product Description
PA1-H52D3	Human	HEK293	Human PAR1 Full Length Protein, Flag,His Tag (Detergent)
PA1-H52P6	Human	HEK293	Human PAR1 Full Length Protein (VLP)
PA1-HF2G5	Human	HEK293	Fluorescent Human PAR1 Full Length Protein (VLP)

Total: 3

PAR1 Background

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants.

PAR1 Synonyms

F2R,coagulation factor II thrombin receptor,CF2R, HTR, PAR-1, PAR1, TR

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Rusalatide	TRAP-508; TP-508	Phase 1 Clinical	Baylor College Of Medicine, University Of Texas Medical Branch	Radius Fractures; Respiratory Distress Syndrome, Adult	Details
Andropaxar-39	Andropaxar 39; Andropaxar-39	Phase 1 Clinical	Shandong Qidu Pharmaceutical Co Ltd, Shandong University	Cardiovascular Diseases	Details
GP-2102	GP-2102; GP2102	Phase 1 Clinical	Nanjing Gritpharma Co Ltd	Dermatitis, Atopic	Details