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PAR2

PAR2 詳細

英語名	Protease-activated receptor-2	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	Receptor， PAR-2，F2RL1，Thrombin receptor-like 1，G-protein coupled receptor 11，F2R Like Trypsin Receptor 1，PAR2，GPR11，Protease-Activated Receptor 2，Coagulation Factor II (Thrombin) Receptor-Like 1，Proteinase-Activated Receptor-2，Proteinase-activated receptor 2，Coagulation factor II receptor-like 1
研究＆開発段階	Phase 2 Clinical

英語名	Protease-activated receptor-2
ターゲットの別称	Receptor， PAR-2，F2RL1，Thrombin receptor-like 1，G-protein coupled receptor 11，F2R Like Trypsin Receptor 1，PAR2，GPR11，Protease-Activated Receptor 2，Coagulation Factor II (Thrombin) Receptor-Like 1，Proteinase-Activated Receptor-2，Proteinase-activated receptor 2，Coagulation factor II receptor-like 1
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 2 Clinical

PAR2 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
- (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
PA2-H52P7	Human	HEK293	Human PAR2 Full Length Protein (VLP)

総数量1

PAR2バックグランド

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

PAR2分子の別称

PAR2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
MEDI-0618	MEDI-0618; MEDI0618; ABBV-2002; ABBV2002	Phase 2 Clinical	Astrazeneca Plc	Chronic Pain; Migraine Disorders	詳細
TEV-56192	TEV-56192	Phase 1 Clinical	Teva Pharmaceutical Industries Ltd	Nervous System Diseases	詳細
OA-235i	OA-235i	Phase 1 Clinical	Oasis Pharmaceuticals LLC	Metabolic Dysfunction-Associated Steatotic Liver Disease	詳細