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PD-L2

PD-L2 詳細

英語名	Programmed death-ligand 2	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
研究＆開発段階	Phase 3 Clinical

英語名	Programmed death-ligand 2
ターゲットの別称	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 3 Clinical

PD-L2 製品リスト

属性
Protein (8)
製品ライブラリ
オンライン (8)
種
Human (5)Mouse (3)
タグ
His Tag (2)Fc Tag (2)Mouse IgG Fc Tag (1)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)
マーカー
Unconjugated (5)Biotin-labeled (3)

製品番号	種	発現システム	製品説明
HOT PD2-H5220	Human	HEK293	Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)
HOT PD2-H82E8	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag (recommended for biopanning)
HOT PD2-H82F6	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag™ (MALS verified)
HOT PD2-M52E3	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, His Tag (MALS verified)
HOT PD2-M82E3	Mouse	HEK293	Biotinylated Mouse PD-L2 / B7-DC Protein, His,Avitag™ (MALS verified)
PD2-H5251	Human	HEK293	Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)
PD2-H52A5	Human	HEK293	Human PD-L2 / B7-DC Protein, Mouse IgG1 Fc Tag
PD2-M5254	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, Fc Tag

総数量8

PD-L2バックグランド

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2分子の別称

PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
CA-170	CA-170; AUPM-170	Phase 3 Clinical	Aurigene	Carcinoma, Non-Small-Cell Lung; Neoplasms; Solid tumours	詳細
IMGS-001	IMGS-001	Phase 1 Clinical	The University Of Texas MD Anderson Cancer Center	Colorectal Neoplasms; Neoplasms; Prostatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	詳細
68Ga-Mirc415		Clinical	Beijing Cancer Hospital	Lung Neoplasms	詳細

レビュー

1***32019-10-11
0評価
Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)
ACROBiosystem's proteins have high purity. They totally meet our requirements. Most importantly, repeatability among batches is very good, and the quality control is great. Thank you!
1***22019-10-12
1評価
Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)
I purchased the PD-L2 protein for ELISA related experiments. Coating the protein into a well plate, and then adding antibody molecules to incubate with biotin-PD1. I could obtain good stable and repeatable data.