言語を選択
新規登録

PLGF

PLGF 詳細

英語名Placental Growth Factor市販薬剤の数13
治験薬の数11ターゲットの別称PGFL，Placental Growth Factor-Like，SHGC-10760，D12S1900，PlGF-2，PIGF，Placenta growth factor，PlGF，PGF，Placental Growth Factor，Placental Growth Factor， Vascular Endothelial Growth Factor-Related Protein
研究＆開発段階Approved
英語名Placental Growth Factor
ターゲットの別称PGFL，Placental Growth Factor-Like，SHGC-10760，D12S1900，PlGF-2，PIGF，Placenta growth factor，PlGF，PGF，Placental Growth Factor，Placental Growth Factor， Vascular Endothelial Growth Factor-Related Protein
市販薬剤の数13
治験薬の数11
研究＆開発段階Approved

PLGF 製品リスト

  • 属性

    Protein (6)

  • 製品ライブラリ

    オンライン (6)

  • 種

    Human (4)Rhesus macaque (1)Mouse (1)

  • タグ

    His Tag (4)Fc Tag (2)

  • マーカー

    Unconjugated (6)

製品番号種発現システム製品説明タンパク質の構造純度特性
HOT
PGF-H5229
Human
HEK293
Human PLGF / PGF (19-170) Protein, His Tag
HOT
PGF-H5255
Human
HEK293
Human PLGF / PGF (19-221) Protein, Fc Tag (MALS verified)
HOT
PGF-H5256
Human
HEK293
Human PLGF / PGF (19-149) Protein, Fc Tag (MALS verified)
HOT
PGF-H52H5
Human
HEK293
Human PLGF / PGF (19-149) Protein, His Tag (MALS verified)
PGF-M52H0
Mouse
HEK293
Mouse PLGF / PGF (19-158) Protein, His Tag
PGF-R52H0
Rhesus macaque
HEK293
Rhesus macaque PLGF / PGF (19-170) Protein, His Tag
総数量6
  • 1

PLGFバックグランド

Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

PLGF分子の別称

PGF,PLGF,PlGF,PGFL,SHGC-10760

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
Aflibercept biosimilar (CinnaGen)Phase 3 ClinicalCinnagenMacular Degeneration
詳細
4D-1504D-150Phase 3 Clinical4d Molecular Therapeutics IncDiabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Shilpa Biologicals)SBDM-03Phase 3 ClinicalShilpa Biologicals Pvt LtdWet Macular Degeneration
詳細
Aflibercept Biosimilar(Rophibio)RBS-001Phase 3 ClinicalRophibio IncMacular Degeneration; Wet Macular Degeneration
詳細
Aflibercept biosimiliar (Jingze Biotechnology)JZB05; JZB-05Phase 3 ClinicalChengdu Zeyan Biotechnology Co Ltd, Shanghai Jingze Biotechnology Co LtdDiabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Retinal Vein Occlusion
詳細
Aflibercept biosimilar (Sam Chun Dang Pharm)SCD-411Phase 3 ClinicalSam Chun Dang Pharm Co LtdMacular Degeneration; Wet Macular Degeneration
詳細
Anti-placental growth factor monoclonal antibodyαPlGF; R-7334; TB-403; RG-7334; THR-317; RO-5323441Phase 2 ClinicalBioinvent International Ab, ThrombogenicsCarcinoma, Hepatocellular; Colorectal Neoplasms; Diabetes Mellitus; Diabetic Retinopathy; Glioblastoma; Macular Degeneration; Macular Edema; Medulloblastoma; Ovarian Neoplasms; Retinal Telangiectasis; Solid tumours
詳細
PB-101PB-101Phase 1 ClinicalPanolos Bioscience IncCarcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Neoplasms; Solid tumours; Stomach Neoplasms
詳細
EB-105EB-105Phase 1 ClinicalEluminex Biosciences (Suzhou) LtdDiabetic macular oedema; Diabetic Retinopathy
詳細
Aflibercept biosimilar(Generium)GNR-098Phase 1 ClinicalGenerium PharmaceuticalsMacular Degeneration
詳細
Aflibercept biosimilar (Zein Bioteccnology)Phase 1 ClinicalZein Bioteccnology Co LtdDiabetic macular oedema
詳細

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
Aflibercept Biosimilar (Alteogen)ALT-L9ApprovedAlteogen Inc, Kissei Pharmaceutical Co LtdEUDiabetic macular oedema; Choroidal Neovascularization; Macular Edema; Retinal Vein Occlusion; Wet Macular DegenerationBiolitec Pharma Ltd2025-09-15Choroidal Neovascularization; Diabetic macular oedema; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Momenta/Mylan)M-710; MYL-1701PApprovedMomenta, Mylan NvYESAFILIEUMyopia, Degenerative; Diabetic Retinopathy; Retinal Vein Occlusion; Diabetes Complications; Macular EdemaViatris Ltd2023-09-15Diabetes Complications; Diabetic macular oedema; Diabetic Retinopathy; Macular Edema; Myopia, Degenerative; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Qilu Pharmaceutical)QL-1207; QL1207HApprovedQilu Pharmaceutical Co Ltd卓初明Mainland ChinaMacular Degeneration; Diabetic macular oedemaQilu Pharmaceutical Co Ltd2023-12-13Diabetic macular oedema; Macular Degeneration; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Amgen)ABP-938ApprovedAmgen IncPAVBLUUnited StatesDiabetic Retinopathy; Macular Edema; Wet Macular Degeneration; Diabetic macular oedemaAmgen Inc2024-08-23Choroidal Neovascularization; Diabetes Complications; Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Vascular Diseases; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Zaklady)SDC411; SDC-411ApprovedZaklady Farmaceutyczne Polpharma SAVgenfliEUChoroidal Neovascularization; Retinal Vein Occlusion; Wet Macular Degeneration; Macular Edema; Diabetic macular oedema; Diabetes ComplicationsZaklady Farmaceutyczne Polpharma SA2025-08-14Choroidal Neovascularization; Diabetes Complications; Diabetic macular oedema; Macular Edema; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
AfliberceptBAY-865321; BAT-86-5321ApprovedBayer AG, Regeneron Pharmaceuticals IncEylea, 艾力雅United StatesMacular Degeneration; Macular EdemaRegeneron Pharmaceuticals Inc2011-11-18Carcinoma, Non-Small-Cell Lung; Cataract; Central Serous Chorioretinopathy; Choroid Diseases; Choroidal Neovascularization; Colonic Neoplasms; Colorectal Neoplasms; Corneal Neovascularization; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic macular oedema; Diabetic Retinopathy; Drug-Related Side Effects and Adverse Reactions; Eye Diseases; Glaucoma, Neovascular; Lymphoma, Non-Hodgkin; Macular Degeneration; Macular Edema; Multiple Myeloma; Myopia, Degenerative; Neoplasm Metastasis; Neoplasms; Polypoidal choroidal vasculopathy; Prostatic Neoplasms; Rectal Neoplasms; Retinal Degeneration; Retinal Diseases; Retinal Vein Occlusion; Retinitis Pigmentosa; Retinopathy of Prematurity; Vitreous Hemorrhage; Wet Macular Degeneration
詳細
Aflibercept Biosimilar (Alvotech Swiss)AVT-29; AVT-06ApprovedAlvotech Swiss AgMynzepliEUWet Macular Degeneration; Macular Edema; Choroidal Neovascularization; Diabetes Complications; Retinal Vein OcclusionStada Arzneimittel Ag, null2025-08-18Choroidal Neovascularization; Diabetes Complications; Diabetic macular oedema; Eye Diseases; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Vascular Diseases; Wet Macular Degeneration
詳細
Aflibercept biosimilar (HEXAL/Sandoz)SOK-583A1; SOK583A1; SOK-583ApprovedHexal, SandozENZEEVU, AfqlirUnited StatesWet Macular DegenerationSandoz Inc2024-08-09Diabetes Complications; Macular Degeneration; Macular Edema; Retinal Diseases; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Celltrion)CT-P42ApprovedCelltrion IncEydenzeltSouth KoreaWet Macular Degeneration; Diabetic macular oedemaCelltrion Inc2024-05-30Choroidal Neovascularization; Diabetes Complications; Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Ziv-afliberceptAVE-0005; BAY-865321ApprovedRegeneron Pharmaceuticals Inc, SanofiZaltrapUnited StatesColorectal NeoplasmsSanofi-Aventis U.S. Llc2012-08-03Adenocarcinoma, Follicular; Ascites; Astrocytoma; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Papillary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Glioblastoma; Glioma; Gliosarcoma; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Leukemia, Myelomonocytic, Chronic; Lung Diseases; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Metastatic breast cancer; Multiple Endocrine Neoplasia Type 1; Multiple Myeloma; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases; Neoplasm Metastasis; Neoplasms; Oligodendroglioma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Rectal Neoplasms; Retinal Vein Occlusion; Skin Melanoma; Small Cell Lung Carcinoma; Solid tumours; Thyroid
詳細
Aflibercept biosimilar (Bioeq)FYB-203ApprovedFormycon AGAHZANTIVE, BaiamaUnited StatesDiabetic Retinopathy; Macular Edema; Wet Macular Degeneration; Diabetic macular oedema; Retinal Vein Occlusion; Macular DegenerationFormycon AG2024-06-28Choroidal Neovascularization; Diabetes Complications; Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Aflibercept biosimilar (Samsung Bioepis)SB-15; AM003; SB15ApprovedSamsung Bioepis Co LtdOPUVIZ, Opuviz, AFILIVUUnited StatesDiabetic macular oedema; Macular Edema; Wet Macular Degeneration; Diabetic RetinopathySamsung Bioepis Co Ltd2024-05-20Diabetes Complications; Diabetic macular oedema; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Retinal Vein Occlusion; Wet Macular Degeneration
詳細
Aflibercept Biosimilar (Boan Biopharma/Luye Pharma）LY-09004; BA-9101; OT-702ApprovedShandong Boan Biotechnology Co Ltd博优景Mainland ChinaWet Macular Degeneration; Diabetic macular oedemaShandong Boan Biotechnology Co Ltd2025-11-25Diabetic macular oedema; Macular Degeneration; Wet Macular Degeneration
詳細
  • 詳細
  • 製品リスト
  • 市販薬剤に関する情報
  • 治験薬に関する情報
共有：

採用情報法的規制サイトマッププライバシーポリシー利用規約
ウェブサイトに関するフィードバック
お問い合わせ

お問い合わせ
グローバル：+1 800-810-0816(Toll Free)

メールアドレス
order.jp@acrobiosystems.com

アクロバイオシステムズ株式会社
〒101-0051
東京都千代田区神田神保町1-32-8