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Properdin

Properdin 詳細

英語名	Properdin	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	Complement factor P，CFP
研究＆開発段階	Phase 2 Clinical

英語名	Properdin
ターゲットの別称	Complement factor P，CFP
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 2 Clinical

Properdin 製品リスト

属性
Protein (3)
製品ライブラリ
オンライン (3)
種
Human (1)Mouse (1)Rhesus macaque (1)
タグ
His Tag (3)
マーカー
Unconjugated (3)

製品番号	種	発現システム	製品説明
HOT PRN-H52H3	Human	HEK293	Human Properdin Protein, His Tag
PRN-M52H5	Mouse	HEK293	Mouse Properdin Protein, His Tag
PRN-R52H6	Rhesus macaque	HEK293	Rhesus macaque Properdin Protein, His Tag

総数量3

Properdinバックグランド

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

Properdin分子の別称

Properdin,Complement factor P,CFP,PFC

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Tarperprumig	ALXN-1820	Phase 2 Clinical	Alexion Pharmaceuticals Inc	Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	詳細
NM-5072	NM5072; NM-5072	Phase 1 Clinical	NovelMed Therapeutics Inc	Atypical Hemolytic Uremic Syndrome; Eye Diseases; Hemoglobinuria, Paroxysmal	詳細