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ROBO4

ROBO4 製品リスト

属性
Protein (3)
製品ライブラリ
オンライン (3)
種
Human (2)Mouse (1)
タグ
His Tag & Avi Tag (1)His Tag (2)
マーカー
Biotin-labeled (1)Unconjugated (2)

製品番号	種	発現システム	製品説明
RO4-H52H3	Human	HEK293	Human ROBO4 Protein, His Tag (MALS verified)
RO4-H82E3	Human	HEK293	Biotinylated Human ROBO4 Protein, His,Avitag™ (MALS verified)
RO4-M52H3	Mouse	HEK293	Mouse ROBO4 Protein, His Tag (MALS verified)

総数量3

ROBO4バックグランド

Roundabout homolog 4 (ROBO4) is also known as Magic roundabout (MRB) and ECSM4, which belongs to the immunoglobulin superfamily or ROBO family. ROBO4 contains 2 fibronectin type-III domains and 2 Ig-like C2-type (immunoglobulin-like) domains. ROBO4 is specifically expressed in endothelial cells and is also expressed at sites of angiogenesis in different tumor types. ROBO4 / MRB is the receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. ROBO-4 may mediate the inhibition of primary endothelial cell migration by Slit proteins.