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SCARB1

SCARB1 詳細

英語名	Scavenger receptor class B member 1	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	CLA1，SRB1，SCARB1，Scavenger Receptor Class B Member 1，CD36 Antigen (Collagen Type I Receptor， Thrombospondin Receptor)-Like 1，CD36 And LIMPII Analogous 1，CD36L1，CLA-1，SR-BI，Collagen Type I Receptor， Thrombospondin Receptor-Like 1，Scavenger Receptor Class B， Member 1，Scavenger Receptor Class B Type III，CD36 Antigen-Like 1，HDLQTL6
研究＆開発段階	Preclinical

英語名	Scavenger receptor class B member 1
ターゲットの別称	CLA1，SRB1，SCARB1，Scavenger Receptor Class B Member 1，CD36 Antigen (Collagen Type I Receptor， Thrombospondin Receptor)-Like 1，CD36 And LIMPII Analogous 1，CD36L1，CLA-1，SR-BI，Collagen Type I Receptor， Thrombospondin Receptor-Like 1，Scavenger Receptor Class B， Member 1，Scavenger Receptor Class B Type III，CD36 Antigen-Like 1，HDLQTL6
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

SCARB1 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
Fc Tag (1)His Tag & Avi Tag (1)
マーカー
Unconjugated (1)Biotin-labeled (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
SC1-H5258	Human	HEK293	Human SCARB1 / SR-B1 Protein, Fc Tag
SC1-H82E5	Human	HEK293	Biotinylated Human SCARB1 / SR-B1 Protein, His,Avitag™ (MALS verified)

総数量2

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SCARB1バックグランド

Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.