SIGIRR
SIGIRR 製品リスト
- 属性
Protein (1)
- 製品ライブラリ
オンライン (1)
- 種
Human (1)
- タグ
Fc Tag (1)
- マーカー
Unconjugated (1)
| 製品番号 | 種 | 発現システム | 製品説明 | タンパク質の構造 | 純度 | 特性 |
|---|---|---|---|---|---|---|
 Human | HEK293 | Human SIGIRR Protein, Fc Tag (MALS verified) |  |  |
総数量1
- 1
SIGIRRバックグランド
Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- 製品リスト