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Siglec-7

Siglec-7 詳細

英語名	Sialic acid-binding Ig-like lectin 7	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	CDw328，AIRM-1，Adhesion inhibitory receptor molecule 1，D-siglec，QA79 membrane protein，CD328
研究＆開発段階	Preclinical

英語名	Sialic acid-binding Ig-like lectin 7
ターゲットの別称	CDw328，AIRM-1，Adhesion inhibitory receptor molecule 1，D-siglec，QA79 membrane protein，CD328
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

Siglec-7 製品リスト

属性
Protein (4)
製品ライブラリ
オンライン (4)
種
Human (4)
タグ
His Tag (1)His Tag & Avi Tag (1)Fc Tag (2)
マーカー
Unconjugated (3)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
HOT SG7-H5225	Human	HEK293	Human Siglec-7 / CD328 Protein, His Tag (MALS verified)
HOT SG7-H82E7	Human	HEK293	Biotinylated Human Siglec-7 / CD328 Protein, His,Avitag™ (MALS & SPR verified)
HOT SI7-H5257	Human	HEK293	Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag, low Endotoxin (MALS verified)
SI7-H5258	Human	HEK293	Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag, low Endotoxin (MALS verified)

総数量4

Siglec-7バックグランド

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.