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SLC1A2

SLC1A2 詳細

英語名	Excitatory amino acid transporter 2	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	GLT1，Glutamate/aspartate transporter II，Sodium-dependent glutamate/aspartate transporter 2，Solute carrier family 1 member 2，SLC1A2，EAAT2
研究＆開発段階	Phase 2 Clinical

英語名	Excitatory amino acid transporter 2
ターゲットの別称	GLT1，Glutamate/aspartate transporter II，Sodium-dependent glutamate/aspartate transporter 2，Solute carrier family 1 member 2，SLC1A2，EAAT2
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 2 Clinical

SLC1A2 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag & Flag Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
SL2-H52D6	Human	HEK293	Human SLC1A2 Protein, Flag,His Tag (Detergent)

総数量1

SLC1A2バックグランド

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

SLC1A2分子の別称

DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
[18F]RP-115	[18F]RP-115	Phase 2 Clinical	Rio pharmaceuticals Inc	Alzheimer Disease; Dementia; Frontotemporal Dementia	詳細
iQ-007	iQ-007	Phase 1 Clinical	iQure Pharma Inc	Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Neuralgia	詳細

レビュー

E***a2026-04-29
0評価
Human SLC1A2 Protein, Flag,His Tag (Detergent)
We used this a POC and it worked in some assays where we got informative data. It is great to see detergent-stabilized proteins becoming more available commercially.