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Stathmin 1

Stathmin 1 詳細

英語名	Stathmin	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
研究＆開発段階	Phase 1 Clinical

英語名	Stathmin
ターゲットの別称	Protein Pr22，Phosphoprotein p19，LAP18，C1orf215，STMN1，Stathmin 1，Oncoprotein 18，Leukemia-Associated Phosphoprotein P18，Stathmin 1/Oncoprotein 18，Metablastin，Prosolin，Chromosome 1 Open Reading Frame 215，Testicular Tissue Protein Li 189，Transmembrane Protein C1orf215，Phosphoprotein 19，Stathmin，PP17，PR22，Op18，Pp19，Lag，SMN，FLJ32206
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 1 Clinical

Stathmin 1 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
ST1-H5149	Human	E. coli	Human Stathmin 1 / STMN1 Protein, His Tag

総数量1

Stathmin 1バックグランド

Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.