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TACI

TACI 詳細

英語名	Tumor necrosis factor receptor superfamily member 13B	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	Transmembrane activator and CAML interactor，CD267，TACI
研究＆開発段階	Preclinical

英語名	Tumor necrosis factor receptor superfamily member 13B
ターゲットの別称	Transmembrane activator and CAML interactor，CD267，TACI
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

TACI 製品リスト

属性
Protein (6)Cell (1)
製品ライブラリ
オンライン (7)
種
Human (7)
タグ
Fc Tag & Avi Tag (1)Fc Tag (2)His Tag (1)- (2)His Tag & Avi Tag (1)
マーカー
Biotin-labeled (3)Unconjugated (3)- (1)

製品番号	種	発現システム	製品説明
HOT TAI-H52H3	Human	HEK293	Human TACI / TNFRSF13B Protein, His Tag, low endotoxin
CHEK-ATF197	Human	HEK293	Human TACI (Luc) HEK293 Reporter Cell
TAI-H5253	Human	HEK293	Human TACI / TNFRSF13B (R119A, R122A) Protein, Fc Tag (MALS verified)
TAI-H5254	Human	HEK293	Human TACI / TNFRSF13B Protein, Fc Tag (HPLC verified)
TAI-H82E3	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, His,Avitag™ (MALS verified)
TAI-H82F6	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, Fc,Avitag™
TAL-H82F3	Human	HEK293	Biotinylated Human TACI / TNFRSF13B Protein, Fc,Avitag™ (MALS verified)

総数量7

TACIバックグランド

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.