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TNFR1

TNFR1 詳細

英語名	Tumor necrosis factor receptor superfamily member 1A	市販薬剤の数	0
治験薬の数	2	ターゲットの別称	Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60
研究＆開発段階	Phase 3 Clinical

英語名	Tumor necrosis factor receptor superfamily member 1A
ターゲットの別称	Tumor necrosis factor receptor 1，TNF-R1，Tumor necrosis factor receptor type I，TNF-RI，TNFR-I，CD120a，TNF Receptor Superfamily Member 1A，TNFAR，Tumor Necrosis Factor Receptor Superfamily Member 1A，TNF-R-I，TNF-R55，TNFR60，TNF-R，TNFR1，Tumor Necrosis Factor Receptor Superfamily， Member 1A，Tumor Necrosis Factor Receptor 1A Isoform Beta，Tumor Necrosis Factor Binding Protein 1，Tumor Necrosis Factor Receptor Type 1，Tumor Necrosis Factor Receptor Type I，Tumor Necrosis Factor-Alpha Receptor，Tumor Necrosis Factor Receptor 1，CD120a Antigen，TNFRSF1A，TNFR55，P55-R，TBP1，FPF，TBPI，p55，p60
市販薬剤の数	0
治験薬の数	2
研究＆開発段階	Phase 3 Clinical

TNFR1 製品リスト

属性
Protein (11)
製品ライブラリ
オンライン (11)
種
Human (6)Human & Mouse (2)Porcine (1)Cynomolgus (1)Mouse (1)
タグ
His Tag (5)Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (4)
マーカー
Unconjugated (6)Biotin-labeled (5)

製品番号	種	発現システム	製品説明
TN1-H5222	Human	HEK293	Human TNFR1 / CD120a / TNFRSF1A Protein, His Tag, low endotoxin (MALS verified)
TN1-H5251	Human	HEK293	Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag (MALS verified)
TN1-H82E4	Human	HEK293	Biotinylated Human TNFR1 / CD120a / TNFRSF1A Protein, His,Avitag™ (MALS verified)
TN1-H82E5	Human	HEK293	Biotinylated Human TNFR1 / CD120a / TNFRSF1A (30-82) Protein, His,Avitag™ (HPLC verified)
TN1-H82E6	Human	HEK293	Biotinylated Human TNFR1 / CD120a / TNFRSF1A (30-211) Protein, His,Avitag™ (MALS verified)
TN1-H82F3	Human	HEK293	Biotinylated Human TNFR1 / CD120a / TNFRSF1A Protein, Fc,Avitag™ (MALS verified)
TN1-M52H3	Mouse	HEK293	Mouse TNFR1 / CD120a / TNFRSF1A Protein, His Tag (MALS verified)
TN1-C52H3	Cynomolgus	HEK293	Cynomolgus TNFR1 / CD120a / TNFRSF1A Protein, His Tag (MALS verified)
TN1-H52H3	Human & Mouse	HEK293	Human & Mouse TNFR1 / CD120a / TNFRSF1A (30-125 & 126-212) Protein, His Tag (MALS verified)
TN1-H52H4	Human & Mouse	HEK293	Human & Mouse TNFR1 / CD120a / TNFRSF1A (30-82 & 83-212) Protein, His Tag (MALS verified)

総数量11

お問い合わせ

TNFR1バックグランド

Tumor necrosis factor receptor 1 (TNF-R1) is also known as Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), TNFAR, CD antigen CD120a, which belongs to the tumor necrosis factor receptor superfamily. TNF-R1 contains one death domain and four TNFR-Cys repeats. TNF-R1 is the receptor of TNFSF2 / TNF-alpha and homotrimeric TNFSF1 / lymphotoxin - alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNF-R1 contributes to the induction of non - cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Defects in TNFRSF1A are the cause of familial hibernian fever (FHF).

TNFR1分子の別称

TNFR1,CD120a,TNFRSF1A,FPF,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR55,TNFR60,p55,p60

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Ofranergene obadenovec	GT-111; VB-111	Phase 3 Clinical	Vascular Pharmaceuticals Inc	Colorectal Neoplasms; Glioblastoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Thyroid Carcinoma, Anaplastic	詳細
Atrosab		Phase 1 Clinical	Celonic	Inflammation	詳細

レビュー

E***a2024-11-13
0評価
Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag (MALS verified)
I was able to get this protein shipped overnight and use it for Octet and SPR experiments. Quality is amazing and the biotinylated protein works great!
1***22019-10-10
0評価
Human TNFR1 / CD120a / TNFRSF1A Protein, Fc Tag (MALS verified)
The quality of TNFR1 protein is pretty good. I performed the SDS-PAGE. The result shown as below is similar to the result on ACRO's official website. The purity is good, and the position is also the same.