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TSHR

TSHR 詳細

英語名	Thyroid stimulating hormone receptor	市販薬剤の数	3
治験薬の数	6	ターゲットの別称	TSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
研究＆開発段階	Approved

英語名	Thyroid stimulating hormone receptor
ターゲットの別称	TSHR，Thyroid Stimulating Hormone Receptor，LGR3，Thyroid-Stimulating Hormone Receptor，Seven Transmembrane Helix Receptor，Thyrotropin Receptor-I， HTSHR-I，Thyrotropin Receptor，TSH Receptor，HTSHR-I，TSH-R，Receptors， Thyrotropin，CHNG1
市販薬剤の数	3
治験薬の数	6
研究＆開発段階	Approved

TSHR 製品リスト

属性
Cell (3)Protein (2)
製品ライブラリ
オンライン (5)
種
Human (5)
タグ
- (5)
マーカー
- (3)Unconjugated (1)Biotin-labeled (1)

製品番号	種	発現システム	製品説明
CHEK-ATF187	Human	HEK293	Human TSHR (Luc) HEK293 Reporter Cell
CHEK-ATP086	Human	HEK293	HEK293/Human TSHR Stable Cell Line
SCCHO-ATP085	Human	CHO	CHO/Human TSHR Stable Cell Line
AI Compatible TSR-H52P3	Human	HEK293	Human TSHR Full Length Protein (VLP)
TSR-H82P3	Human	HEK293	Biotinylated Human TSHR Full Length Protein (VLP)

総数量5

お問い合わせ

TSHRバックグランド

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

TSHR分子の別称

TSHR,TSH-R,LGR3,TSH R

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Anti-thyroid stimulating hormone receptor chimeric antigen receptor T cell therapy (Innovative Cellular Therapeutics)	ICTCAT-023	Phase 2 Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	詳細
ZG-001(Zhigen)	ZG-001(Zhigen); JH-001	Phase 2 Clinical	Hunan Warner Pharmaceutical Factory Chiral Medicine Co Ltd, Hunan Warrant Pharmaceutical Co Ltd, Shanghai Zhigen Pharmaceutical Technology Co Ltd	Depressive Disorder; Depressive Disorder, Major	詳細
ICTCAR-051	ICTCAR-051	Phase 1 Clinical	Innovative Cellular Therapeutics Co Ltd	Solid tumours; Thyroid Neoplasms	詳細
KSP-0914		Phase 1 Clinical	Kissei Pharmaceutical Co Ltd	Graves Disease	詳細
GensSci098	GenSci098; GenSci-098; GensSci-098; GensSci098; GS-098; YB-101	Phase 1 Clinical	Changchun GeneScience Pharmaceuticals Co Ltd	Goiter; Graves Disease; Graves Ophthalmopathy	詳細
ICTCAR-TC	ICTCAR-TC	Clinical	Innovative Cellular Therapeutics Co Ltd	Thyroid Neoplasms	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Thyrotropin alfa	rh-TSH; MRrhTSH; rhTSH-M	Approved	Genzyme Corp	Thyrogen	United States	Thyroid Neoplasms	Genzyme Corp	1998-11-30	Diagnostic agents; Goiter, Nodular; Thyroid Neoplasms	詳細
Recombinant human thyrotropin (Zelgen Biosciences)		Approved	Suzhou Zelgen Biosciences Co Ltd	赛诺璟, 泽速宁	Mainland China	Thyroid Neoplasms	Suzhou Zelgen Biopharmaceuticals Co Ltd	2026-01-05	Thyroid Neoplasms	詳細
Recombinant human thyroid stimulating hormone(Smartnuclide)	SNA-001; SNA001; KN040; KN-040	Approved	Smartnuclide Biopharma	智舒嘉	Mainland China	Thyroid Neoplasms	Smartnuclide Biopharma	2024-04-02	Thyroid Neoplasms	詳細