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TSLP

TSLP 詳細

英語名Thymic stromal lymphopoietin市販薬剤の数1
治験薬の数28ターゲットの別称Thymic stromal lymphopoietin，TSLP
研究＆開発段階Approved
英語名Thymic stromal lymphopoietin
ターゲットの別称Thymic stromal lymphopoietin，TSLP
市販薬剤の数1
治験薬の数28
研究＆開発段階Approved

TSLP 製品リスト

  • 属性

    Protein (17)Kits (2)

  • 製品ライブラリ

    オンライン (19)

  • 種

    Human (13)Mouse (2)Cynomolgus (3)Rat (1)

  • タグ

    His Tag & Avi Tag (4)His Tag (8)Mouse IgG Fc Tag (1)- (2)Fc Tag (2)Fc Tag & Avi Tag (2)

  • マーカー

    Biotin-labeled (6)Unconjugated (10)- (2)PE Labeled (1)

製品番号種発現システム製品説明タンパク質の構造純度特性
HOT
TSP-H5243
Human
HEK293
Human TSLP Protein (R127A, R130A), His Tag, low endotoxin (MALS verified)
HOT
TSP-H52Hb
Human
HEK293
Human TSLP Protein, His Tag, premium grade
HOT
TSP-H82Eb
Human
HEK293
Biotinylated Human TSLP Protein, His,Avitag™ (MALS verified)
HOT
TSP-M52H8
Mouse
HEK293
Mouse TSLP Protein, His Tag (MALS verified)
HOT
TSP-C52H4
Cynomolgus
HEK293
Cynomolgus TSLP (R127A, R130S) Protein, His Tag, low endotoxin (HPLC verified)
HOT
TSP-C52H8
Cynomolgus
HEK293
Cynomolgus TSLP Protein, His Tag (MALS verified)
CEA-C074
Human
-
Human TSLP ELISA Kit
FRT-P012
Human
-
Human TSLP / IL-7Rα & TSLP R Inhibitor Screening Kit (TR-FRET)
TSP-H5253
Human
HEK293
Human TSLP Protein, Fc Tag, low endotoxin (MALS verified)
TSP-H5254
Human
HEK293
Human TSLP (R127A, R130A) Protein, Fc Tag, low endotoxin (MALS verified)
総数量19
  • 1
  • 2

TSLPバックグランド

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.

TSLP分子の別称

TSLP

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
QL-2302QL2302; QL-2302Phase 3 ClinicalQilu Pharmaceutical Co LtdAsthma
詳細
GB-0895GB-0895Phase 3 ClinicalGenerate Biomedicines IncAsthma; Immune System Diseases; Pulmonary Disease, Chronic Obstructive
詳細
TilrekimigPF-07275315Phase 3 ClinicalPfizer IncAsthma; Dermatitis, Atopic; Pulmonary Disease, Chronic Obstructive
詳細
LunsekimigSAR-443765Phase 3 ClinicalSanofiAsthma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Dermatitis, Atopic; Inflammation; Pulmonary Disease, Chronic Obstructive
詳細
BosakitugTQC-2731; BSI-045B; TQC2731; ATI-045Phase 3 ClinicalBiosion IncAsthma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Dermatitis; Dermatitis, Atopic; Eczema; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Sinusitis
詳細
SHR-1905SHR-1905; AIO-001; GSK-5784283Phase 3 ClinicalJiangsu Hengrui Medicine Co LtdAsthma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Dermatitis, Atopic; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Diseases; Sinusitis
詳細
CM-326CM-326Phase 3 ClinicalKeymed Biosciences Co LtdAsthma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Dermatitis, Atopic; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Sinusitis
詳細
QX-008NQX-008N; QX008N; JKN-2401; JKN2401; SNCA008; SNCA-008Phase 3 ClinicalQyuns Therapeutics Co LtdAsthma; Pulmonary Disease, Chronic Obstructive
詳細
SolrikitugNSI-8226; MK-8226Phase 2 ClinicalMerck & Co IncAsthma; Dermatitis, Atopic; Eosinophilic Esophagitis; Hypertension; Pulmonary Disease, Chronic Obstructive
詳細
EcleralimabCSJ-117; NOV-14Phase 2 ClinicalNovartis Pharma AgAsthma; Pulmonary Disease, Chronic Obstructive
詳細
HBM-9378HBM-9378; SKB378; SKB-378; A-378; WIN378; WIN-378Phase 2 ClinicalHarbour Biomed, Sichuan Kelun-Biotech Biopharmaceutical Co LtdAsthma; Pulmonary Disease, Chronic Obstructive
詳細
CM-512CM512; CM-512Phase 2 ClinicalKeymed Biosciences Co LtdAsthma; Bronchiectasis; Chronic rhinosinusitis with nasal polyps (CRSwNP); Chronic Urticaria; Dermatitis, Atopic; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic; Sinusitis
詳細
IBI-3002IBI3002; IBI-3002Phase 2 ClinicalAsthma; Dermatitis, Atopic
詳細
MG-ZG122MG-ZG122; MGZG122Phase 2 ClinicalShanghai Mabgeek Biotechnology Co LtdAsthma; Pulmonary Disease, Chronic Obstructive
詳細
AZD-8630AZD-8630; AMG-104Phase 2 ClinicalAmgen Inc, Astrazeneca PlcAsthma
詳細
TAVO-101TAVO-101; TAVO101Phase 2 ClinicalTavotek Biotherapeutics (Hong Kong) LtdDermatitis, Atopic; Hypersensitivity
詳細
PF-06342674RN-168; PF-6342674; PF-06342674; ZB-168Phase 1 ClinicalPfizer IncDiabetes Mellitus, Type 1; Multiple Sclerosis
詳細
APG273APG273; APG-273Phase 1 ClinicalApogee Therapeutics IncAsthma; Pulmonary Disease, Chronic Obstructive
詳細
HBM-7575HBM-7575; SKB575; SKB-575; HBM7575Phase 1 ClinicalHarbour BiomedDermatitis, Atopic; Inflammation
詳細
WIN-027QX027N; QX-027-N; WIN027; WIN-027Phase 1 ClinicalQyuns Therapeutics Co LtdAsthma; Dermatitis, Atopic
詳細
HB-0056HB-0056; HB0056Phase 1 ClinicalShanghai Huaota Biopharmaceutical Co Ltd, Zhejiang Huahai Pharmaceutical Co LtdAsthma; Dermatitis, Atopic; Idiopathic Pulmonary Fibrosis; Pulmonary Disease, Chronic Obstructive
詳細
APG-333APG333; APG-333; PR018; PR-018Phase 1 ClinicalApogee Therapeutics IncAsthma
詳細
SAR-444765SAR444765; SAR-444765Phase 1 ClinicalSanofiInflammation
詳細
BSI-502BSI-502; ATI-052Phase 1 ClinicalBiosion IncAutoimmune Diseases of the Nervous System; Inflammation
詳細
CDX-622CDX-622Phase 1 ClinicalCelldex Therapeutics IncAsthma; Fibrosis; Hypersensitivity; Inflammation
詳細
STSA-1201STSA-1201; STSA1201Phase 1 ClinicalStaidson(Beijing) Biopharmaceuticals Co LtdAsthma
詳細
LQ043HLQ043HPhase 1 ClinicalShanghai Novamab Biopharmaceuticals Co LtdAsthma
詳細
GR2002GR2002Phase 1 ClinicalGenrix (Shanghai) Biopharmaceutical Co LtdAsthma; Dermatitis, Atopic; Nasal Polyps; Sinusitis
詳細

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
TezepelumabMEDI-9929; AMG-157ApprovedAmgen IncTezspireUnited StatesAsthmaAstrazeneca Ab2021-12-17Anaphylaxis; Asthma; Bronchial Diseases; Carcinoma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Chronic Urticaria; Dermatitis, Atopic; Eosinophilic Esophagitis; Granulomatosis with Polyangiitis; Hypersensitivity; Hypersensitivity, Immediate; Immune System Diseases; Lung Diseases; Lung Diseases, Obstructive; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Respiratory Hypersensitivity; Respiratory Tract Diseases; Sinusitis
詳細

レビュー

  • S***n2023-06-10
    2評価
    Mouse TSLP Protein, His Tag (MALS verified)
    We got the TSLP recombinant protein from your company. The plan was to stimulate cell in vitro to see if it can induce a TH2 response. Your company offers the most cost effective option for the TSLP protein and with good customer service and express shipping. So far we do see some level of responses in the cells, we will perform more testing to validate the effects. The quality of the protein seems quite good and worth trying.
  • 詳細
  • 製品リスト
  • 市販薬剤に関する情報
  • レビュー
  • 治験薬に関する情報
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